Gisadenafil
Gisadenafil is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target cGMP-specific 3',5'-cyclic phosphodiesterase.
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Drug
General
| Drug common name | Gisadenafil |
| INN | gisadenafil |
| Description | Gisadenafil is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target cGMP-specific 3',5'-cyclic phosphodiesterase. |
| Classification | Small molecule |
| Drug class | phosphodiesterase type 5 inhibitors (PDE5) inhibitors: (PDE5) inhibitors containing a sulfonamide moiety |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCOc1ncc(S(=O)(=O)N2CCN(CC)CC2)cc1-c1nc2c(CC)n(CCOC)nc2c(=O)[nH]1 |
Identifiers
| PDB | — |
| CAS-ID | 334826-98-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1928262 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB11902 |
| UNII ID | S6G4R7DI1C (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
PDE5A
PDE5A
Organism
Homo sapiens
Gene name
PDE5A
Gene synonyms
PDE5
NCBI Gene ID
Protein name
cGMP-specific 3',5'-cyclic phosphodiesterase
Protein synonyms
CGB-PDE, cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase, cGMP-binding cGMP-specific phosphodiesterase, cGMP-specific phosphodiesterase PDE5A2, cGMP-specific phosphodiesterase type 5A, phosphodiesterase 5A, cGMP-specific, phosphodiesterase isozyme 5
Uniprot ID
Mouse ortholog
Pde5a (242202)
cGMP-specific 3',5'-cyclic phosphodiesterase (Q8CG03)
Variants
No data
Financial
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Trends
PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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