Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Breast neoplasms | D001943 | EFO_0003869 | C50 | 5 | 2 | 1 | — | 1 | 8 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Colorectal neoplasms | D015179 | — | — | 1 | 2 | — | — | — | 2 |
Non-small-cell lung carcinoma | D002289 | — | — | 2 | 1 | — | — | — | 2 |
Endometrial neoplasms | D016889 | EFO_0004230 | — | 1 | 1 | — | — | — | 2 |
Triple negative breast neoplasms | D064726 | — | — | 2 | 1 | — | — | — | 2 |
Myelodysplastic syndromes | D009190 | — | D46 | — | 1 | — | — | — | 1 |
Myeloid leukemia acute | D015470 | — | C92.0 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 4 | — | — | — | — | 4 |
Head and neck neoplasms | D006258 | — | — | 2 | — | — | — | — | 2 |
Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | — | — | — | — | 1 |
Squamous cell neoplasms | D018307 | — | — | 1 | — | — | — | — | 1 |
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | — | — | — | — | 1 |
Small cell lung carcinoma | D055752 | — | — | 1 | — | — | — | — | 1 |
Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Drug common name | Gedatolisib |
INN | gedatolisib |
Description | Gedatolisib (PF-05212384) is an experimental drug for treatment of cancer in development by Celcuity, Inc. The mechanism of action is accomplished by binding the different p110 catalytic subunit isoforms of PI3K and the kinase site of mTOR.
|
Classification | Small molecule |
Drug class | phosphatidylinositol 3-kinase (PI3K) inhibitors |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CN(C)C1CCN(C(=O)c2ccc(NC(=O)Nc3ccc(-c4nc(N5CCOCC5)nc(N5CCOCC5)n4)cc3)cc2)CC1 |
PDB | — |
CAS-ID | 1197160-78-3 |
RxCUI | — |
ChEMBL ID | CHEMBL592445 |
ChEBI ID | — |
PubChem CID | 44516953 |
DrugBank | — |
UNII ID | 96265TNH2R (ChemIDplus, GSRS) |