Ganaplacide
Ganaplacide is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
9 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Malaria | D008288 | EFO_0001068 | B54 | 4 | 4 | 1 | — | — | 9 |
| Falciparum malaria | D016778 | EFO_0007444 | B50 | — | 3 | 1 | — | — | 4 |
| Body weight | D001835 | EFO_0004338 | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Vivax malaria | D016780 | EFO_0007445 | B51 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Ganaplacide |
| INN | ganaplacide |
| Description | Ganaplacide (development code KAF156) is a drug in development by Novartis for the purpose of treating malaria. It belongs to the class of the imidazolopiperazines. It has shown activity against the Plasmodium falciparum and Plasmodium vivax forms of the malaria parasite.
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| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)c2nc(-c3ccc(F)cc3)c(Nc3ccc(F)cc3)n2CCN1C(=O)CN |
Identifiers
| PDB | — |
| CAS-ID | 1261113-96-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2058833 |
| ChEBI ID | — |
| PubChem CID | 49856296 |
| DrugBank | — |
| UNII ID | 85VMN9JU7A (ChemIDplus, GSRS) |
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Trends
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Safety
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