Optimark(gadoversetamide)
Optimark (gadoversetamide) is a small molecule pharmaceutical. Gadoversetamide was first approved as Optimark on 1999-12-08. It has been approved in Europe to treat magnetic resonance imaging.
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Gadoversetamide
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| OPTIMARK | Liebel-Flarsheim | N-020937 DISCN | 1999-12-08 | 4 products, RLD |
| OPTIMARK | Liebel-Flarsheim | N-020975 DISCN | 1999-12-08 | 1 products, RLD |
| OPTIMARK IN PLASTIC CONTAINER | Liebel-Flarsheim | N-020976 DISCN | 1999-12-08 | 4 products, RLD |
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General
| Drug common name | Gadoversetamide |
| INN | gadoversetamide |
| Description | Gadoversetamide is a gadolinium coordination entity that consists of Gd(3+) coordinated to 3,6,9-triazaundecadiamide in which each of the amide nitrogens is substituted by a 2-methoxyethyl group and in which the nitrogens at positions 3, 6, and 9 are each substituted by carboxylatomethyl group. The gadolinium is coordinated to the three tertiary amino groups as well as to the carboxylate groups. A white odourless powder that is freely soluble in water, gadoversetamide has paramagnetic properties and is used as a contrast agent in magnetic resonance imaging. It distributes mainly in extracellular fluid, but does not cross the blood-brain barrier. It is used particularly in imaging the brain, spine and liver. It has a role as a MRI contrast agent. |
| Classification | Small molecule |
| Drug class | gadolinium derivatives (principally for diagnostic use) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 131069-91-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1200457 |
| ChEBI ID | 31644 |
| PubChem CID | 444013 |
| DrugBank | DB00538 |
| UNII ID | RLM74T3Z9D (ChemIDplus, GSRS) |
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