Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cutaneous leishmaniasis | D016773 | — | B55.1 | — | 1 | — | — | — | 1 |
Leishmaniasis | D007896 | EFO_0005044 | B55 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Covid-19 | D000086382 | — | — | 1 | — | — | — | — | 1 |
Fever | D005334 | HP_0001945 | R50.9 | 1 | — | — | — | — | 1 |
Yellow fever | D015004 | — | A95 | 1 | — | — | — | — | 1 |
Virus diseases | D014777 | — | B34 | 1 | — | — | — | — | 1 |
Marburg virus disease | D008379 | EFO_0007358 | A98.3 | 1 | — | — | — | — | 1 |
Ebola hemorrhagic fever | D019142 | EFO_0007243 | A98.4 | 1 | — | — | — | — | 1 |
Infections | D007239 | EFO_0000544 | — | 1 | — | — | — | — | 1 |
Communicable diseases | D003141 | — | — | 1 | — | — | — | — | 1 |
Filoviridae infections | D018702 | EFO_0007273 | — | 1 | — | — | — | — | 1 |
Drug common name | GALIDESIVIR |
INN | galidesivir |
Description | Galidesivir (BCX4430, immucillin-A) is an antiviral drug, an adenosine analog (a type of nucleoside analog). It was developed by BioCryst Pharmaceuticals with funding from NIAID, originally intended as a treatment for hepatitis C, but subsequently developed as a potential treatment for deadly filovirus infections such as Ebola virus disease and Marburg virus disease, as well as Zika virus. Currently, galidesivir is under phase 1 human trial in Brazil for coronavirus.
|
Classification | Small molecule |
Drug class | antivirals: adenosine analogs acting as RNA polymerase inhibitors |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | Nc1ncnc2c([C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)c[nH]c12 |
PDB | — |
CAS-ID | 222631-44-9 |
RxCUI | — |
ChEMBL ID | CHEMBL1236524 |
ChEBI ID | — |
PubChem CID | 69211190 |
DrugBank | — |
UNII ID | OLF97F86A7 (ChemIDplus, GSRS) |