Fotemustine
Fotemustine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
14 clinical trials
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Melanoma | D008545 | — | — | — | 4 | 4 | — | — | 8 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | — | — | 2 | — | — | 2 |
| Neoplasms | D009369 | — | C80 | — | — | 2 | — | — | 2 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | — | — | 1 | — | — | 1 |
| Follicular lymphoma | D008224 | — | C82 | — | — | 1 | — | — | 1 |
| Uveal neoplasms | D014604 | EFO_1001230 | — | — | — | 1 | — | — | 1 |
| Germ cell and embryonal neoplasms | D009373 | — | — | — | — | 1 | — | — | 1 |
| Neuroendocrine tumors | D018358 | EFO_1001901 | D3A.8 | — | — | 1 | — | — | 1 |
| Neoplasms by histologic type | D009370 | — | — | — | — | 1 | — | — | 1 |
| Primitive neuroectodermal tumors | D018242 | — | — | — | — | 1 | — | — | 1 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioblastoma | D005909 | EFO_0000515 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Fotemustine |
| INN | fotemustine |
| Description | Diethyl (1-{[(2-chloroethyl)(nitroso)carbamoyl]amino}ethyl)phosphonate is a member of the class of N-nitrosoureas that is ethyl diethylphosphonate in the hydrogen at position 1 of the ethyl group attached to the phosphorus has been replaced by a [(2-chloroethyl)(nitroso)carbamoyl]amino group. It is an organic phosphonate, a member of N-nitrosoureas and an organochlorine compound. |
| Classification | Small molecule |
| Drug class | antineoplastics (chloroethylamine derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCOP(=O)(OCC)C(C)NC(=O)N(CCCl)N=O |
Identifiers
| PDB | — |
| CAS-ID | 191219-77-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL549386 |
| ChEBI ID | — |
| PubChem CID | 104799 |
| DrugBank | DB04106 |
| UNII ID | GQ7JL9P5I2 (ChemIDplus, GSRS) |
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Safety
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297 adverse events reported
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