Fospropofol
Lusedra (fospropofol) is a small molecule pharmaceutical. Fospropofol was first approved as Lusedra on 2008-12-12.
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Clinical
Clinical Trials
27 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anesthesia | D000758 | — | — | — | — | 1 | 1 | — | 2 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | 1 | — | 2 |
| Orthopedic procedures | D019637 | — | — | — | — | — | 1 | — | 1 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | 1 | — | 1 |
| Elective surgical procedures | D017558 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colonic polyps | D003111 | — | K63.5 | — | 3 | 2 | — | — | 4 |
| Colonoscopy | D003113 | — | — | — | 3 | 2 | — | — | 4 |
| Bronchoscopy | D001999 | — | — | — | — | 2 | — | — | 2 |
| Angioplasty | D017130 | — | — | — | — | 1 | — | — | 1 |
| Coronary angiography | D017023 | — | — | — | — | 1 | — | — | 1 |
| Conscious sedation | D016292 | — | — | — | — | 1 | — | — | 1 |
| Arthroscopy | D001182 | — | — | — | — | 1 | — | — | 1 |
| Bunion | D000071378 | — | M21.61 | — | — | 1 | — | — | 1 |
| Carpal tunnel syndrome | D002349 | EFO_0004143 | G56.0 | — | — | 1 | — | — | 1 |
| Osteotomy | D010027 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Critical illness | D016638 | — | — | — | 2 | — | — | — | 2 |
| Coronary disease | D003327 | — | — | — | 1 | — | — | — | 1 |
| Coronary artery disease | D003324 | — | I25.1 | — | 1 | — | — | — | 1 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | 1 | — | — | — | 1 |
| Coronary artery bypass | D001026 | EFO_0003776 | — | — | 1 | — | — | — | 1 |
| Artificial respiration | D012121 | — | — | — | 1 | — | — | — | 1 |
| Intubation | D007440 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Interstitial cystitis | D018856 | EFO_1000869 | N30.1 | — | — | — | — | 1 | 1 |
| Cystitis | D003556 | EFO_1000025 | N30 | — | — | — | — | 1 | 1 |
| Invasive hydatidiform mole | D002820 | — | D39.2 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Fospropofol |
| INN | fospropofol |
| Description | Fospropofol (INN), often used as the disodium salt (trade name Lusedra) is an intravenous sedative-hypnotic agent. It is currently approved for use in sedation of adult patients undergoing diagnostic or therapeutic procedures such as endoscopy.
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| Classification | Small molecule |
| Drug class | phosphoro-derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)c1cccc(C(C)C)c1OCOP(=O)(O)O |
Identifiers
| PDB | — |
| CAS-ID | 258516-89-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201766 |
| ChEBI ID | — |
| PubChem CID | 3038498 |
| DrugBank | DB06716 |
| UNII ID | LZ257RZP7K (ChemIDplus, GSRS) |
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Safety
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Adverse Events
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