Fosphenytoin
Cerebyx, Fosphenytoin (fosphenytoin) is a small molecule pharmaceutical. Fosphenytoin was first approved as Cerebyx on 1996-08-05. It is used to treat epilepsy, seizures, and status epilepticus in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| nervous system diseases | D009422 |
| signs and symptoms pathological conditions | D013568 |
Trade Name
FDA
EMA
Cerebyx, Fosphenytoin (discontinued: Fosphenytoin, Sesquient)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| cerebyx | New Drug Application | 2025-08-28 |
| fosphenytoin | ANDA | 2023-03-31 |
| fosphenytoin sodium | ANDA | 2026-02-18 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| epilepsy | EFO_0000474 | D004827 | G40.9 |
| seizures | — | D012640 | G40.4 |
| status epilepticus | EFO_0008526 | D013226 | G41 |
Agency Specific
FDA
EMA
No data
Clinical
Clinical Trials
16 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Seizures | D012640 | — | G40.4 | — | 1 | — | 2 | 2 | 5 |
| Traumatic brain injuries | D000070642 | — | S06 | — | — | — | 2 | 1 | 3 |
| Brain injuries | D001930 | — | S06.9 | — | — | — | 2 | 1 | 3 |
| Status epilepticus | D013226 | EFO_0008526 | G41 | — | — | 2 | 1 | — | 3 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | 1 | 1 | 2 |
| Subarachnoid hemorrhage | D013345 | EFO_0000713 | I60 | — | — | — | 1 | 1 | 2 |
| Emergencies | D004630 | — | — | — | — | — | 1 | — | 1 |
| Intracranial hemorrhages | D020300 | EFO_0000551 | I62 | — | — | — | 1 | — | 1 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | 1 | — | 1 |
| Brain ischemia | D002545 | EFO_0003883 | I67.82 | — | — | — | 1 | — | 1 |
Show 5 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Epilepsy | D004827 | EFO_0000474 | G40.9 | — | — | 2 | — | — | 2 |
| Acute pain | D059787 | — | R52 | — | — | 1 | — | — | 1 |
| Herpes zoster | D006562 | EFO_0006510 | B02 | — | — | 1 | — | — | 1 |
| Herpes simplex | D006561 | — | B00 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | 1 | 2 | — | — | — | 2 |
| Leukemia | D007938 | — | C95 | 1 | 1 | — | — | — | 1 |
| Neuroblastoma | D009447 | EFO_0000621 | — | 1 | 1 | — | — | — | 1 |
| Anemia | D000740 | EFO_0004272 | D64.9 | 1 | 1 | — | — | — | 1 |
| Immunologic deficiency syndromes | D007153 | — | D84.9 | 1 | 1 | — | — | — | 1 |
| Myelodysplastic syndromes | D009190 | — | D46 | — | 1 | — | — | — | 1 |
| Myeloid leukemia acute | D015470 | — | C92.0 | — | 1 | — | — | — | 1 |
| Myeloproliferative disorders | D009196 | — | D47.1 | — | 1 | — | — | — | 1 |
| Primary myelofibrosis | D055728 | — | D47.4 | — | 1 | — | — | — | 1 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | — | 1 | — | — | — | 1 |
Show 6 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | — | 1 |
| Glioma | D005910 | EFO_0000520 | — | 1 | — | — | — | — | 1 |
| Gliosarcoma | D018316 | — | — | 1 | — | — | — | — | 1 |
| Astrocytoma | D001254 | EFO_0000271 | — | 1 | — | — | — | — | 1 |
| Oligodendroglioma | D009837 | EFO_0000631 | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Brain diseases | D001927 | — | G93.40 | — | — | — | — | 1 | 1 |
| Neuralgia | D009437 | EFO_0009430 | — | — | — | — | — | 1 | 1 |
| Trigeminal neuralgia | D014277 | EFO_1001219 | G50.0 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Fosphenytoin |
| INN | fosphenytoin |
| Description | Fosphenytoin is an imidazolidine-2,4-dione. |
| Classification | Small molecule |
| Drug class | phosphoro-derivatives; antiepileptics (hydantoin derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C1NC(c2ccccc2)(c2ccccc2)C(=O)N1COP(=O)(O)O |
Identifiers
| PDB | — |
| CAS-ID | 93390-81-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201336 |
| ChEBI ID | 5165 |
| PubChem CID | 56339 |
| DrugBank | DB01320 |
| UNII ID | B4SF212641 (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 2,040 documents
View more details
Safety
Black-box Warning
Black-box warning for: Cerebyx, Fosphenytoin, Fosphenytoin sodium
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
1,940 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use