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Drug ReportsFosmanogepix
Fosmanogepix
Fosmanogepix is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
14 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MycosesD009181B35-B4951219
CandidemiaD058387EFO_1001282213
Invasive candidiasisD058365EFO_1001283B37112
Invasive hydatidiform moleD002820D39.211
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Invasive fungal infectionsD0000727421113
Covid-19D000086382U07.111
AspergillosisD001228EFO_0007157B4411
Pulmonary aspergillosisD055732EFO_100183411
CandidiasisD002177B3711
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LeukemiaD007938C9511
Myeloid leukemia acuteD015470C92.011
NeutropeniaD009503D7011
Myeloid leukemiaD007951C9211
Hepatic insufficiencyD04855011
Healthy volunteers/patients11
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
InfectionsD007239EFO_000054411
Communicable diseasesD00314111
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameFosmanogepix
INNfosmanogepix
Description
Fosmanogepix is an experimental antifungal drug being developed by Amplyx Pharmaceuticals (now currently by Pfizer and Basilea) It is being investigated for its potential to treat various fungal infections including aspergillosis, candidaemia, and coccidioidomycosis.
Classification
Small molecule
Drug classphosphoro-derivatives
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Structure (InChI/SMILES or Protein Sequence)
Nc1c(-c2cc(Cc3ccc(COc4ccccn4)cc3)no2)ccc[n+]1COP(=O)([O-])O
Identifiers
PDB
CAS-ID1169701-00-1
RxCUI
ChEMBL IDCHEMBL4297591
ChEBI ID
PubChem CID44123754
DrugBankDB15183
UNII ID1XQ871489P (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 646 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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