PharmaKB logo
Company Reports
Company Reports
Drug Reports
Drug Reports
Disease Reports
Disease Reports
Sets
Sets
Favorites
Favorites
Log in
Log in
AboutPricing
Drug ReportsFosfomycin
Fosfomycin
Fosfomycin Tromethamine, Monurol (fosfomycin) is a small molecule pharmaceutical. Fosfomycin was first approved as Monurol on 1996-12-19. It is used to treat escherichia coli infections, gram-positive bacterial infections, klebsiella infections, proteus infections, and serratia infections amongst others in the USA.
Download report
Favorite
Searched
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Plot placeholder
Mock data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
urogenital diseasesD000091642
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
fosfomycin tromethamineANDA2024-10-22
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01X: Other antibacterials in atc
— J01XX: Other antibacterials in atc
— J01XX01: Fosfomycin
S: Sensory organ drugs
— S02: Otologicals
— S02A: Antiinfective drugs, otologic
— S02AA: Antiinfectives
— S02AA17: Fosfomycin
HCPCS
No data
Clinical
Clinical Trials
74 clinical trials
View more details
Plot placeholder
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
InfectionsD007239EFO_0000544—145181036
Urinary tract infectionsD014552EFO_0003103N39.016516733
Communicable diseasesD003141———2412724
PneumoniaD011014EFO_0003106—12—137
CystitisD003556EFO_1000025N30——1247
BacteremiaD016470EFO_0003033R78.81——1236
SepsisD018805HP_0100806A41.9—1—236
Bacterial infectionsD001424—A491——146
Intraabdominal infectionsD059413—————123
EndocarditisD004696HP_0100584————123
Show 18 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———2—1——3
NeutropeniaD009503—D70——1—12
GonorrheaD006069DOID_7551A54——1——1
Escherichia coli infectionsD004927EFO_1001318B96.20——1——1
NeoplasmsD009369—C80—11——1
FeverD005334HP_0001945R50.9——1——1
Febrile neutropeniaD064147————1——1
HyperthermiaD000084462————1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bacterial pneumoniaD018410EFO_1001272J15.9—2——13
AppendicitisD001064EFO_0007149K37—2———2
ToxemiaD014115———1——12
Urinary bladder neoplasmsD001749—C67—1———1
Urologic surgical proceduresD013520———1———1
Colonic neoplasmsD003110—C18—1———1
AdenomaD000236———1———1
Neonatal sepsisD000071074HP_0040187——1———1
Ulcerative colitisD003093EFO_0000729K5111———1
ColitisD003092EFO_0003872K52.911———1
Show 1 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OsteomyelitisD010019EFO_0003102M861———12
Multiple drug resistanceD018432——1———12
Pseudomonas infectionsD011552EFO_0001076A41.521————1
Disease resistanceD060467——1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HemorrhageD006470MP_0001914R58————22
Heart failureD006333HP_0001635I50————22
HypertensionD006973EFO_0000537I10————22
MenorrhagiaD008595EFO_0003945N92.0————22
Hemophilia aD006467EFO_0007267D66————22
PainD010146EFO_0003843R52————22
HyperaldosteronismD006929HP_0011736E26————22
Pulmonary arterial hypertensionD000081029——————22
HypokalemiaD007008HP_0002900E87.6————22
Sleep initiation and maintenance disordersD007319—F51.01————22
Show 66 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameFosfomycin
INNfosfomycin
Description
Fosfomycin is a phosphonic acid having an (R,S)-1,2-epoxypropyl group attached to phosphorus. It has a role as an antimicrobial agent and an EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor. It is an epoxide and a member of phosphonic acids. It is functionally related to a phosphonic acid. It is a conjugate acid of a (1R,2S)-epoxypropylphosphonate(1-).
Classification
Small molecule
Drug classphosphoro-derivatives; antibiotics (Streptomyces strain)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
C[C@@H]1O[C@@H]1P(=O)(O)O
Identifiers
PDB—
CAS-ID23155-02-4
RxCUI—
ChEMBL IDCHEMBL1757
ChEBI ID28915
PubChem CID446987
DrugBankDB00828
UNII ID2N81MY12TE (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Fosfomycin
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Plot placeholder
Mock data
Subscribe for the real data
Additional graphs summarizing 13,375 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Plot placeholder
Mock data
Subscribe for the real data
1,761 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use