Fluprednisolone
Alphadrol (fluprednisolone) is a small molecule pharmaceutical. Fluprednisolone was first approved as Alphadrol on 1982-01-01. It is used to treat skin diseases in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| skin and connective tissue diseases | D017437 |
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Drug Products
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Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Fluprednisolone
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| ALPHADROL | Pharmacia & Upjohn | N-012259 DISCN | 1982-01-01 | 1 products |
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Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| skin diseases | — | D012871 | L00-L99 |
Agency Specific
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Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Inflammation | D007249 | MP_0001845 | — | — | — | 3 | — | — | 3 |
| Vomiting | D014839 | HP_0002013 | R11.1 | — | — | 2 | — | — | 2 |
| Nausea | D009325 | HP_0002018 | R11.0 | — | — | 2 | — | — | 2 |
| Cataract | D002386 | HP_0000518 | H26.9 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Keratoconjunctivitis sicca | D007638 | EFO_1000906 | — | — | 1 | — | — | — | 1 |
| Dry eye syndromes | D015352 | — | H04.12 | — | 1 | — | — | — | 1 |
| Eye diseases | D005128 | EFO_0003966 | H44 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Fluprednisolone |
| INN | fluprednisolone |
| Description | Alphadrol (fluprednisolone) is a small molecule pharmaceutical. Fluprednisolone was first approved as Alphadrol on 1982-01-01. It is used to treat skin diseases in the USA. |
| Classification | Small molecule |
| Drug class | steroids (not prednisolone derivatives); prednisone and prednisolone derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@]12C[C@H](O)[C@H]3[C@@H](C[C@H](F)C4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO |
Identifiers
| PDB | — |
| CAS-ID | 53-34-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1200774 |
| ChEBI ID | 34474 |
| PubChem CID | 5876 |
| DrugBank | — |
| UNII ID | 9H05937G3X (ChemIDplus, GSRS) |
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Safety
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