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Drug ReportsFlupentixol
Flupentixol
Flupentixol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against D(2) dopamine receptor and D(1A) dopamine receptor. In addition, it is known to target D(3) dopamine receptor and D(1B) dopamine receptor.
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Financial
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Events Timeline
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Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
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Indications
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Agency Specific
FDA
EMA
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ATC Codes
N: Nervous system drugs
— N05: Psycholeptics
— N05A: Antipsychotics
— N05AF: Thioxanthene derivatives, antipsychotic
— N05AF01: Flupentixol
HCPCS
No data
Clinical
Clinical Trials
24 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SchizophreniaD012559EFO_0000692F20—1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameFlupentixol
INNflupentixol
Description
Cis-flupenthixol is a flupenthixol in which the double bond adopts a cis-configuration. It has a role as a dopaminergic antagonist. It is a conjugate base of a cis-flupenthixol(2+).
Classification
Small molecule
Drug classTypical antipsychotic
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
OCCN1CCN(CC/C=C2/c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1
Identifiers
PDB—
CAS-ID53772-82-0
RxCUI—
ChEMBL IDCHEMBL54661
ChEBI ID10454
PubChem CID5281881
DrugBankDB00875
UNII ID21HMQ851IS (ChemIDplus, GSRS)
Target
Agency Approved
DRD2
DRD2
DRD1
DRD1
Organism
Homo sapiens
Gene name
DRD2
Gene synonyms
NCBI Gene ID
Protein name
D(2) dopamine receptor
Protein synonyms
Dopamine D2 receptor, seven transmembrane helix receptor
Uniprot ID
Mouse ortholog
Drd2 (13489)
D(2) dopamine receptor (Q0VGH9)
Alternate
DRD3
DRD3
DRD5
DRD5
Organism
Homo sapiens
Gene name
DRD3
Gene synonyms
NCBI Gene ID
Protein name
D(3) dopamine receptor
Protein synonyms
Dopamine D3 receptor, essential tremor 1
Uniprot ID
Mouse ortholog
Drd3 (13490)
D(3) dopamine receptor (P30728)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 3,135 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,617 adverse events reported
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