Flupentixol
Flupentixol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against D(2) dopamine receptor and D(1A) dopamine receptor. In addition, it is known to target D(3) dopamine receptor and D(1B) dopamine receptor.
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
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Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Flupentixol |
| INN | flupentixol |
| Description | Cis-flupenthixol is a flupenthixol in which the double bond adopts a cis-configuration. It has a role as a dopaminergic antagonist. It is a conjugate base of a cis-flupenthixol(2+). |
| Classification | Small molecule |
| Drug class | Typical antipsychotic |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | OCCN1CCN(CC/C=C2/c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 53772-82-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL54661 |
| ChEBI ID | 10454 |
| PubChem CID | 5281881 |
| DrugBank | DB00875 |
| UNII ID | 21HMQ851IS (ChemIDplus, GSRS) |
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1,834 adverse events reported
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