Brand Name | Status | Last Update |
---|---|---|
ciclopirox 8% / fluconazole 1% / terbinafine hcl 1% | unapproved drug other | 2019-04-24 |
diflucan | New Drug Application | 2023-09-21 |
direct rx | ANDA | 2015-08-03 |
fluconazole | ANDA | 2024-01-24 |
fluconazole 4% / ibuprofen 2% / itraconazole 1% / terbinafine hcl 4% | unapproved drug other | 2019-04-24 |
fluconazole in sodium chloride | ANDA | 2022-01-25 |
Code | Description |
---|---|
J1450 | Injection fluconazole, 200 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hiv infections | D015658 | EFO_0000764 | B20 | 3 | 6 | 6 | 2 | 26 | 42 |
Cryptococcal meningitis | D016919 | EFO_0007228 | B45.1 | 3 | 6 | 5 | 1 | 19 | 31 |
Mycoses | D009181 | — | B35-B49 | 4 | 5 | 10 | 1 | 7 | 27 |
Healthy volunteers/patients | — | — | — | 21 | 1 | — | 1 | 4 | 26 |
Candidiasis | D002177 | — | B37 | 3 | 1 | 10 | 6 | 6 | 25 |
Vulvovaginal candidiasis | D002181 | EFO_0007543 | B37.3 | 1 | 8 | 9 | 3 | 2 | 22 |
Oral candidiasis | D002180 | EFO_0007406 | B37.0 | — | 4 | 3 | 2 | 5 | 14 |
Fungemia | D016469 | — | B49 | — | 1 | 2 | 1 | — | 4 |
Invasive fungal infections | D000072742 | — | — | — | — | — | 2 | 2 | 4 |
Oral lichen planus | D017676 | — | — | — | 1 | — | 3 | — | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Candidemia | D058387 | EFO_1001282 | — | 1 | 3 | 7 | — | — | 10 |
Invasive candidiasis | D058365 | EFO_1001283 | B37 | — | 2 | 6 | — | 1 | 9 |
Neoplasms | D009369 | — | C80 | 5 | 2 | 1 | — | — | 8 |
Myeloid leukemia acute | D015470 | — | C92.0 | 5 | 4 | 1 | — | 1 | 7 |
Hiv | D006678 | — | O98.7 | 1 | 2 | 2 | — | — | 4 |
Leukemia | D007938 | — | C95 | — | 2 | 1 | — | 1 | 4 |
Bacterial vaginosis | D016585 | EFO_0003932 | — | 1 | — | 1 | — | 2 | 4 |
Head and neck neoplasms | D006258 | — | — | 2 | 1 | 1 | — | — | 3 |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 2 | 2 | 1 | — | — | 3 |
Lymphoma | D008223 | — | C85.9 | 2 | — | 1 | — | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Graft vs host disease | D006086 | — | D89.81 | 2 | 1 | — | — | 1 | 4 |
Myelodysplastic syndromes | D009190 | — | D46 | — | 1 | — | — | 2 | 3 |
Stomatitis | D013280 | EFO_1001904 | K12.1 | 1 | 2 | — | — | — | 3 |
Crohn disease | D003424 | EFO_0000384 | K50 | — | 3 | — | — | — | 3 |
Vulvovaginitis | D014848 | EFO_1001240 | N76.0 | — | 3 | — | — | — | 3 |
Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 1 | 1 | — | — | 1 | 2 |
Hematopoietic stem cell transplantation | D018380 | — | — | — | 1 | — | — | 1 | 2 |
Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | 1 | — | — | 1 | 2 |
Meningitis | D008581 | HP_0001287 | G03 | — | 1 | — | — | 1 | 2 |
Sporotrichosis | D013174 | EFO_0007494 | B42 | — | 2 | — | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Drug-related side effects and adverse reactions | D064420 | — | T88.7 | 1 | — | — | — | 2 | 3 |
Drug interactions | D004347 | — | — | 3 | — | — | — | — | 3 |
Prostatic neoplasms | D011471 | — | C61 | 1 | — | — | — | 2 | 3 |
Therapeutic equivalency | D013810 | — | — | 3 | — | — | — | — | 3 |
Endometriosis | D004715 | EFO_0001065 | N80 | 2 | — | — | — | — | 2 |
Glioblastoma | D005909 | EFO_0000515 | — | 2 | — | — | — | — | 2 |
Invasive pulmonary aspergillosis | D055744 | — | B44.0 | 2 | — | — | — | — | 2 |
Stem cell transplantation | D033581 | — | — | 1 | — | — | — | — | 1 |
Overactive urinary bladder | D053201 | EFO_1000781 | N32.81 | 1 | — | — | — | — | 1 |
Mantle-cell lymphoma | D020522 | — | C83.1 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hematologic diseases | D006402 | EFO_0005803 | D75.9 | — | — | — | — | 2 | 2 |
Heart failure | D006333 | HP_0001635 | I50 | — | — | — | — | 1 | 1 |
Delirium | D003693 | — | R41.0 | — | — | — | — | 1 | 1 |
White dot syndromes | D000080363 | — | H30.14 | — | — | — | — | 1 | 1 |
Vascular diseases | D014652 | EFO_0004264 | I77 | — | — | — | — | 1 | 1 |
Heart diseases | D006331 | EFO_0003777 | I51.9 | — | — | — | — | 1 | 1 |
Cerebral hemorrhage | D002543 | — | — | — | — | — | — | 1 | 1 |
Subarachnoid hemorrhage | D013345 | EFO_0000713 | I60 | — | — | — | — | 1 | 1 |
Drug monitoring | D016903 | — | — | — | — | — | — | 1 | 1 |
Multiple myeloma | D009101 | — | C90.0 | — | — | — | — | 1 | 1 |
Drug common name | Fluconazole |
INN | fluconazole |
Description | Fluconazole is a member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis. It has a role as a P450 inhibitor, an environmental contaminant and a xenobiotic. It is a difluorobenzene, a conazole antifungal drug, a triazole antifungal drug and a tertiary alcohol. It is functionally related to a 1,3-difluorobenzene. It derives from a hydride of a 1H-1,2,4-triazole. |
Classification | Small molecule |
Drug class | systemic antifungals (miconazole type) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | OC(Cn1cncn1)(Cn1cncn1)c1ccc(F)cc1F |
PDB | — |
CAS-ID | 86386-73-4 |
RxCUI | — |
ChEMBL ID | CHEMBL106 |
ChEBI ID | 46081 |
PubChem CID | 3365 |
DrugBank | DB00196 |
UNII ID | 8VZV102JFY (ChemIDplus, GSRS) |