Floxacillin
Floxacillin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
33 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cellulitis | D002481 | EFO_0003035 | L03.90 | — | — | 2 | 3 | 2 | 7 |
| Staphylococcal infections | D013203 | — | A49.01 | — | 1 | 1 | 2 | 1 | 5 |
| Osteomyelitis | D010019 | EFO_0003102 | M86 | — | 1 | — | 1 | — | 2 |
| Emergencies | D004630 | — | — | — | — | — | 1 | 1 | 2 |
| Bacteremia | D016470 | EFO_0003033 | R78.81 | — | — | — | 1 | 1 | 2 |
| Infectious arthritis | D001170 | EFO_1001351 | M00 | — | — | — | 1 | — | 1 |
| Staphylococcus aureus | D013211 | NCBITaxon_1280 | — | — | — | — | 1 | — | 1 |
| Wound infection | D014946 | — | — | — | — | — | 1 | — | 1 |
| Abscess | D000038 | EFO_0003030 | — | — | — | — | 1 | — | 1 |
| Erysipelas | D004886 | — | A46 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | 1 | 4 | — | 3 | 8 |
| Bacterial infections | D001424 | — | A49 | 1 | — | 1 | — | 3 | 5 |
| Communicable diseases | D003141 | — | — | — | 1 | 3 | — | — | 4 |
| Infectious skin diseases | D012874 | — | — | — | — | 3 | — | — | 3 |
| Bacterial skin diseases | D017192 | — | — | — | — | 3 | — | — | 3 |
| Methicillin-resistant staphylococcus aureus | D055624 | — | — | — | — | 2 | — | — | 2 |
| Sepsis | D018805 | EFO_0001420 | A41.9 | — | — | 1 | — | 1 | 2 |
| Staphylococcal skin infections | D013207 | EFO_1001849 | L00 | — | — | 1 | — | — | 1 |
| Skin diseases | D012871 | — | L00-L99 | — | — | 1 | — | — | 1 |
| Soft tissue infections | D018461 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart valve diseases | D006349 | EFO_0009551 | I08 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Drug interactions | D004347 | — | — | 1 | — | — | — | — | 1 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
| Chronic renal insufficiency | D051436 | — | N18 | 1 | — | — | — | — | 1 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Critical illness | D016638 | — | — | — | — | — | — | 1 | 1 |
| Drug monitoring | D016903 | — | — | — | — | — | — | 1 | 1 |
| Mastitis | D008413 | EFO_1001034 | N61 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Floxacillin |
| INN | flucloxacillin |
| Description | Flucloxacillin is a penicillin compound having a 6beta-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamido] side-chain. It has a role as an antibacterial drug. It is a penicillin and a penicillin allergen. It is a conjugate acid of a flucloxacillin(1-). |
| Classification | Small molecule |
| Drug class | penicillins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1onc(-c2c(F)cccc2Cl)c1C(=O)N[C@@H]1C(=O)N2[C@@H](C(=O)O)C(C)(C)S[C@H]12 |
Identifiers
| PDB | — |
| CAS-ID | 5250-39-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL222645 |
| ChEBI ID | 5098 |
| PubChem CID | 21319 |
| DrugBank | DB00301 |
| UNII ID | 43B2M34G2V (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Safety
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Adverse Events
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2,414 adverse events reported
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