Therapeutic Area | MeSH |
---|---|
cardiovascular diseases | D002318 |
signs and symptoms pathological conditions | D013568 |
Brand Name | Status | Last Update |
---|---|---|
flecainide acetate | ANDA | 2024-10-16 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | 3 | 9 | 14 | 20 | 45 |
Cardiac arrhythmias | D001145 | EFO_0004269 | I49.9 | — | 1 | 4 | 1 | 3 | 9 |
Tachycardia | D013610 | HP_0001649 | R00.0 | — | — | 2 | 3 | 3 | 8 |
Ventricular tachycardia | D017180 | — | I47.2 | — | 1 | 1 | 3 | 1 | 6 |
Premature birth | D047928 | EFO_0003917 | O60 | — | 2 | — | 1 | 1 | 4 |
Ventricular premature complexes | D018879 | — | I49.3 | — | 1 | — | 2 | 1 | 4 |
Brugada syndrome | D053840 | Orphanet_130 | I49.8 | — | — | — | 1 | 2 | 3 |
Stroke | D020521 | EFO_0000712 | I63.9 | — | — | 1 | 1 | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Supraventricular tachycardia | D013617 | HP_0004755 | I47.1 | — | — | 1 | — | 2 | 3 |
Cardiovascular diseases | D002318 | HP_0001626 | — | — | 1 | 2 | — | — | 3 |
Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 1 | 2 | — | — | 3 |
Heart failure | D006333 | HP_0001635 | I50 | — | — | 1 | — | 1 | 2 |
Recurrence | D012008 | — | — | — | 1 | 1 | — | 1 | 2 |
Atrial flutter | D001282 | EFO_0003911 | — | — | — | 1 | — | 1 | 2 |
Coronary disease | D003327 | — | — | — | — | 2 | — | — | 2 |
Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | 2 | — | — | 2 |
Heart arrest | D006323 | EFO_0009492 | I46 | — | — | 2 | — | — | 2 |
Ischemic stroke | D000083242 | — | — | — | — | 2 | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Syndrome | D013577 | — | — | — | 1 | — | — | 2 | 3 |
Arrhythmogenic right ventricular dysplasia | D019571 | Orphanet_247 | I42.8 | — | 1 | — | — | 1 | 2 |
Cardiomyopathies | D009202 | EFO_0000318 | I42 | — | 1 | — | — | 1 | 2 |
Premature cardiac complexes | D005117 | — | I49.40 | — | 1 | — | — | 1 | 2 |
Sleepiness | D000077260 | — | R40.0 | — | 2 | — | — | — | 2 |
Parkinson disease | D010300 | EFO_0002508 | G20 | — | 1 | — | — | — | 1 |
Disorders of excessive somnolence | D006970 | — | G47.1 | — | 1 | — | — | — | 1 |
Narcolepsy | D009290 | HP_0030050 | G47.4 | — | 1 | — | — | — | 1 |
Blood pressure | D001794 | EFO_0004325 | — | — | 1 | — | — | — | 1 |
Pain | D010146 | EFO_0003843 | R52 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sleep deprivation | D012892 | — | F51.12 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Drug-related side effects and adverse reactions | D064420 | — | T88.7 | — | — | — | — | 1 | 1 |
Drug interactions | D004347 | — | — | — | — | — | — | 1 | 1 |
Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | — | — | — | — | 1 | 1 |
Drug common name | Flecainide |
INN | flecainide |
Description | Flecainide is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart). It has a role as an anti-arrhythmia drug. It is a monocarboxylic acid amide, a member of piperidines, an organofluorine compound and an aromatic ether. It is a conjugate base of a flecainide(1+). |
Classification | Small molecule |
Drug class | Ic antiarrhythmic |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | O=C(NCC1CCCCN1)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F |
PDB | — |
CAS-ID | 54143-55-4 |
RxCUI | — |
ChEMBL ID | CHEMBL652 |
ChEBI ID | 75984 |
PubChem CID | 3356 |
DrugBank | DB01195 |
UNII ID | K94FTS1806 (ChemIDplus, GSRS) |