Brand Name | Status | Last Update |
---|---|---|
febuxostat | ANDA | 2025-01-10 |
uloric | New Drug Application | 2023-04-27 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
gout | EFO_0004274 | D006073 | M10 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Gout | D006073 | EFO_0004274 | M10 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Syndrome | D013577 | — | — | 1 | 1 | 1 | — | — | 2 |
Tumor lysis syndrome | D015275 | — | E88.3 | 1 | 1 | 1 | — | — | 2 |
Hematologic neoplasms | D019337 | — | — | — | — | 1 | — | — | 1 |
Drug common name | Febuxostat |
INN | febuxostat |
Description | Febuxostat is a 1,3-thiazolemonocarboxylic acid that is 4-methyl-1,3-thiazole-5-carboxylic acid which is substituted by a 3-cyano-4-(2-methylpropoxy)phenyl group at position 2. It is an orally-active, potent, and selective xanthine oxidase inhibitor used for the treatment of chronic hyperuricaemia in patients with gout. It has a role as an EC 1.17.3.2 (xanthine oxidase) inhibitor. It is an aromatic ether, a nitrile and a 1,3-thiazolemonocarboxylic acid. |
Classification | Small molecule |
Drug class | enzyme inhibitors: xanthine oxidase/dehydrogenase inhibitors |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | Cc1nc(-c2ccc(OCC(C)C)c(C#N)c2)sc1C(=O)O |
PDB | — |
CAS-ID | 144060-53-7 |
RxCUI | — |
ChEMBL ID | CHEMBL1164729 |
ChEBI ID | — |
PubChem CID | 134018 |
DrugBank | DB04854 |
UNII ID | 101V0R1N2E (ChemIDplus, GSRS) |