Brand Name | Status | Last Update |
---|---|---|
vabysmo | Biologic Licensing Application | 2024-12-02 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
diabetic retinopathy | EFO_0003770 | D003930 | — |
Code | Description |
---|---|
J2777 | Injection, faricimab-svoa, 0.1 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Macular edema | D008269 | — | — | — | 2 | 6 | 1 | 3 | 12 |
Macular degeneration | D008268 | EFO_0001365 | H35.30 | 1 | 2 | 4 | 1 | 3 | 11 |
Edema | D004487 | — | R60.9 | — | 2 | 6 | 1 | 1 | 10 |
Wet macular degeneration | D057135 | EFO_0004683 | — | — | — | 4 | 1 | 1 | 6 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Retinal vein occlusion | D012170 | EFO_1001157 | H34.81 | — | — | 2 | — | 2 | 4 |
Choroidal neovascularization | D020256 | — | — | — | 2 | 1 | — | — | 3 |
Pathologic neovascularization | D009389 | — | — | — | 2 | 1 | — | — | 3 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | — | — | 1 | — | — | 1 |
Myopia | D009216 | EFO_0003927 | H52.1 | — | — | 1 | — | — | 1 |
Retinal neovascularization | D015861 | — | H35.05 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Papilledema | D010211 | EFO_1001074 | H35.81 | — | — | — | — | 1 | 1 |
Drug common name | Faricimab |
INN | faricimab |
Description | Faricimab, sold under the brand name Vabysmo, is a monoclonal antibody used for the treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME). Faricimab is the first bispecific monoclonal antibody to target both vascular endothelial growth factor (VEGF) and angiopoietin 2 (Ang-2). By targeting these pathways, faricimab stabilizes blood vessels in the retina. It is given by intravitreal injection (injection into the eye) by an ophthalmologist.
|
Classification | Antibody |
Drug class | monoclonal antibodies |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL4297750 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB15303 |
UNII ID | QC4F7FKK7I (ChemIDplus, GSRS) |