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AboutPricing
Drug ReportsFamotidine
Famotidine
/ Famotidine /, Famotidine, Famotidine /, Pepcid (famotidine) is a small molecule pharmaceutical. Famotidine was first approved as Pepcid on 1986-10-15. It is used to treat duodenal ulcer, dyspepsia, gastroesophageal reflux, heartburn, and helicobacter infections amongst others in the USA. The pharmaceutical is active against histamine H2 receptor.
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Drug
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Safety
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FDA approval date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
neoplasmsD009369
digestive system diseasesD004066
skin and connective tissue diseasesD017437
immune system diseasesD007154
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Famotidine, Pepcid ac (discontinued: Famotidine, Fluxid, Pepcid, Pepcid ac, Pepcid rpd)
Combinations
Famotidine, carbonate, magnesium hydroxide, Famotidine; ibuprofen, Ibuprofen famotidine, Pepcid complete (discontinued: Duexis, Famotidine ibuprofen, Famotidine, carbonate, magnesium hydroxide)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Famotidine
Tradename
Company
Number
Date
Products
PEPCID ACJohnson & JohnsonN-020325 OTC1995-04-28
2 products, RLD
PEPCID ACJohnson & JohnsonN-020801 OTC2007-12-17
1 products, RLD, RS
PEPCID ACJohnson & JohnsonN-020902 OTC1999-08-05
1 products
Show 8 discontinued
Calcium carbonate
+
Famotidine
+
Magnesium hydroxide
Tradename
Company
Number
Date
Products
PEPCID COMPLETEJohnson & JohnsonN-020958 OTC2000-10-16
1 products, RLD, RS
Famotidine
+
Ibuprofen
Tradename
Company
Number
Date
Products
DUEXISHorizon Therapeutics PublicN-022519 DISCN2011-04-23
1 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
acid controllerANDA2024-12-30
acid reducerANDA2024-10-22
acid reducer completeANDA2022-07-19
acid reducer plus antacidANDA2024-12-20
acid reliefANDA2023-10-02
amazon basic care acid reducerANDA2024-05-21
basic care acid reducerANDA2022-04-11
basic care dual action completeANDA2022-07-11
basic care famotidineANDA2020-02-19
basic care heartburn preventionANDA2022-01-05
Show 65 more
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
gastroesophageal refluxEFO_0003948D005764K21
helicobacter infectionsEFO_1000961D016481—
peptic esophagitisEFO_1001095D004942—
stomach ulcer—D013276K25
duodenal ulcerEFO_0004607D004381K26
dyspepsiaEFO_0008533D004415K30
zollinger-ellison syndrome—D015043E16.4
urticariaEFO_0005531D014581L50
heartburn—D006356R12
juvenile arthritisEFO_1002007D001171M08
Show 11 more
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Famotidine / Ibuprofen, Duexis, Horizon
80674512026-07-18DPU-1196
83091272026-07-18DP
83182022026-07-18DP
84499102026-07-18DP
85012282026-07-18U-1196
ATC Codes
A: Alimentary tract and metabolism drugs
— A02: Drugs for acid related disorders
— A02B: Drugs for peptic ulcer and gastro-oesophageal reflux disease (gord)
— A02BA: H2-receptor antagonists
— A02BA03: Famotidine
— A02BA53: Famotidine, combinations
HCPCS
Code
Description
S0028
Injection, famotidine, 20 mg
Clinical
No data
Drug
General
Drug common nameFamotidine
INNfamotidine
Description
Famotidine, sold under the brand name Pepcid among others, is a histamine H2 receptor antagonist medication that decreases stomach acid production. It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. It is taken by mouth or by injection into a vein. It begins working within an hour.
Classification
Small molecule
Drug classH2-receptor antagonists (cimetidine type)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
NC(N)=Nc1nc(CSCC/C(N)=N/S(N)(=O)=O)cs1
Identifiers
PDB—
CAS-ID76824-35-6
RxCUI—
ChEMBL IDCHEMBL902
ChEBI ID4975
PubChem CID5702160
DrugBankDB00927
UNII ID5QZO15J2Z8 (ChemIDplus, GSRS)
Target
Agency Approved
HRH2
HRH2
Organism
Homo sapiens
Gene name
HRH2
Gene synonyms
NCBI Gene ID
3274
Protein name
histamine H2 receptor
Protein synonyms
gastric receptor 1, Gastric receptor I
Uniprot ID
P25021
Mouse ortholog
Hrh2 (15466)
histamine H2 receptor (Q9D282)
Alternate
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
Duexis – Horizon Therapeutics Public
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Estimated US medical usage
Famotidine
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Price per prescription (USD)
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Famotidine
+
Ibuprofen
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Trends
No data
Safety
Black-box Warning
Black-box warning for: Duexis, Ibuprofen and famotidine
Adverse Events
0 adverse events reported
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