Famotidine
/ Famotidine /, Famotidine, Famotidine /, Pepcid (famotidine) is a small molecule pharmaceutical. Famotidine was first approved as Pepcid on 1986-10-15. It is used to treat duodenal ulcer, dyspepsia, gastroesophageal reflux, heartburn, and helicobacter infections amongst others in the USA. The pharmaceutical is active against histamine H2 receptor.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Trade Name
FDA
EMA
Pepcid ac (generic drugs available since 2001-04-16, discontinued: Fluxid, Pepcid, Pepcid rpd)
CombinationsDuexis, Pepcid complete (generic drugs available since 2001-04-16)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Calcium carbonate
+
Famotidine
+
Magnesium hydroxide
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| PEPCID COMPLETE | Johnson & Johnson | N-020958 OTC | 2000-10-16 | 1 products, RLD, RS |
Famotidine
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| PEPCID AC | Johnson & Johnson | N-020325 OTC | 1995-04-28 | 2 products, RLD |
| PEPCID AC | Johnson & Johnson | N-020801 OTC | 2007-12-17 | 1 products, RLD, RS |
| PEPCID AC | Johnson & Johnson | N-020902 OTC | 1999-08-05 | 1 products |
Show 8 discontinued
Famotidine
+
Ibuprofen
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| DUEXIS | Horizon Pharmaceutical | N-022519 RX | 2011-04-23 | 1 products, RLD, RS |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| acid controller | ANDA | 2023-10-13 |
| acid reducer | ANDA | 2022-04-13 |
| acid reducer complete | ANDA | 2022-07-19 |
| acid reducer plus antacid | ANDA | 2022-07-19 |
| acid relief | ANDA | 2023-10-02 |
| basic care acid reducer | ANDA | 2022-04-11 |
| basic care dual action complete | ANDA | 2022-07-11 |
| basic care famotidine | ANDA | 2020-02-19 |
| basic care heartburn prevention | ANDA | 2022-01-05 |
| berkley and jensen famotidine | ANDA | 2023-12-22 |
Show 58 more
Indications
FDA
EMA
Agency Specific
FDA
EMA
No data
HCPCS
Code | Description |
|---|---|
| S0028 | Injection, famotidine, 20 mg |
Clinical
Clinical Trials
138 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | U07.1 | 1 | 7 | 4 | 2 | 5 | 18 |
| Peptic ulcer | D010437 | HP_0004398 | K27 | — | — | 1 | 2 | 3 | 6 |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | 1 | 2 | 2 | 1 | 1 | 5 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 2 | — | — | 1 | — | 3 |
| Heartburn | D006356 | — | R12 | 2 | — | — | 1 | — | 3 |
| Acute coronary syndrome | D054058 | EFO_0005672 | — | — | — | — | 2 | — | 2 |
| Inferior wall myocardial infarction | D056989 | EFO_1000983 | — | — | — | — | 2 | — | 2 |
| Dyspepsia | D004415 | EFO_0008533 | K30 | — | — | — | 2 | — | 2 |
| Stomach ulcer | D013276 | — | K25 | — | — | 1 | 1 | — | 2 |
| Infections | D007239 | EFO_0000544 | — | 1 | — | — | 1 | — | 2 |
Show 13 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 1 | 2 | — | 1 | 3 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | 1 | 1 | — | — | 2 |
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | — | 2 | — | — | 2 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | — | 2 | — | — | 2 |
| Low back pain | D017116 | HP_0003419 | M54.5 | — | — | 2 | — | — | 2 |
| Arthritis | D001168 | HP_0001369 | M05-M14 | — | — | 1 | — | — | 1 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | — | — | 1 | — | — | 1 |
| Head and neck neoplasms | D006258 | — | — | — | — | 1 | — | — | 1 |
| Esophageal neoplasms | D004938 | — | C15 | — | — | 1 | — | — | 1 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | — | — | 1 | — | — | 1 |
Show 4 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stroke | D020521 | EFO_0000712 | I63.9 | — | 1 | — | — | 1 | 2 |
| Laryngomalacia | D055092 | HP_0001601 | — | 1 | 1 | — | — | 1 | 2 |
| Fallopian tube neoplasms | D005185 | — | — | — | 1 | — | — | — | 1 |
| Peritoneal neoplasms | D010534 | — | — | — | 1 | — | — | — | 1 |
| Brain edema | D001929 | EFO_1000845 | G93.6 | — | 1 | — | — | — | 1 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | 1 | — | — | — | 1 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | — | 1 | — | — | — | 1 |
| Eosinophilic esophagitis | D057765 | EFO_0004232 | K20.0 | — | 1 | — | — | — | 1 |
| Pulmonary arterial hypertension | D000081029 | — | — | — | 1 | — | — | — | 1 |
| Dyskinesias | D020820 | HP_0002310 | G24 | — | 1 | — | — | — | 1 |
Show 4 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 20 | — | — | — | 2 | 22 |
| Drug interactions | D004347 | — | — | 2 | — | — | — | — | 2 |
| Biological availability | D001682 | — | — | 2 | — | — | — | — | 2 |
| Neoplasms | D009369 | — | C80 | 2 | — | — | — | — | 2 |
| Hairy cell leukemia | D007943 | — | C91.4 | 1 | — | — | — | — | 1 |
| Autonomic nervous system diseases | D001342 | EFO_0009532 | G90 | 1 | — | — | — | — | 1 |
| Fibrosis | D005355 | — | — | 1 | — | — | — | — | 1 |
| Psoriasis | D011565 | EFO_0000676 | L40 | 1 | — | — | — | — | 1 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 1 | — | — | — | — | 1 |
| Colorectal neoplasms | D015179 | — | — | 1 | — | — | — | — | 1 |
Show 4 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Exercise | D015444 | EFO_0000483 | — | — | — | — | — | 2 | 2 |
| Rhytidoplasty | D015361 | — | — | — | — | — | — | 1 | 1 |
| Delirium | D003693 | — | R41.0 | — | — | — | — | 1 | 1 |
| Cytokine release syndrome | D000080424 | — | D89.83 | — | — | — | — | 1 | 1 |
| Vomiting | D014839 | HP_0002013 | R11.1 | — | — | — | — | 1 | 1 |
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | — | — | — | — | 1 | 1 |
| Diarrhea | D003967 | HP_0002014 | R19.7 | — | — | — | — | 1 | 1 |
| Respiratory sounds | D012135 | HP_0010307 | R06.1 | — | — | — | — | 1 | 1 |
| Post-exercise hypotension | D057774 | EFO_1001828 | — | — | — | — | — | 1 | 1 |
| Postoperative nausea and vomiting | D020250 | EFO_0004888 | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Famotidine |
| INN | famotidine |
| Description | Famotidine, sold under the brand name Pepcid among others, is a histamine H2 receptor antagonist medication that decreases stomach acid production. It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. It is taken by mouth or by injection into a vein. It begins working within an hour.
|
| Classification | Small molecule |
| Drug class | H2-receptor antagonists (cimetidine type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | NC(N)=Nc1nc(CSCC/C(N)=N/S(N)(=O)=O)cs1 |
Identifiers
| PDB | — |
| CAS-ID | 76824-35-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL902 |
| ChEBI ID | 4975 |
| PubChem CID | 5702160 |
| DrugBank | DB00927 |
| UNII ID | 5QZO15J2Z8 (ChemIDplus, GSRS) |
Target
Variants
No data
Financial
Revenue by drug
$
€
£
₣
Duexis – Horizon Therapeutics Public
Mock data
Subscribe for the real data
Subscribe for the real data
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Estimated US medical usage
Famotidine
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Famotidine
+
Ibuprofen
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 6,662 documents
View more details
Safety
Black-box Warning
Black-box warning for: Duexis, Ibuprofen and famotidine
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
10,317 adverse events reported
View more details
© 2020-2023 Collaborative Drug Discovery Inc. (CDD) | Terms of Use