Evofosfamide
Evofosfamide is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
27 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | 1 | — | — | — | 1 |
| Neuroendocrine tumors | D018358 | EFO_1001901 | D3A.8 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Evofosfamide |
| INN | evofosfamide |
| Description | Evofosfamide (INN, USAN; formerly known as TH-302). Is a compound being evaluated in clinical trials for the treatment of multiple tumor types as a monotherapy and in combination with chemotherapeutic agents and other targeted cancer drugs.
|
| Classification | Small molecule |
| Drug class | phosphoro-derivatives; isophosphoramide mustard derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cn1c(COP(=O)(NCCBr)NCCBr)cnc1[N+](=O)[O-] |
Identifiers
| PDB | — |
| CAS-ID | 918633-87-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL260046 |
| ChEBI ID | — |
| PubChem CID | 11984561 |
| DrugBank | DB06091 |
| UNII ID | 8A9RZ3HN8W (ChemIDplus, GSRS) |
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Additional graphs summarizing 625 documents
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Safety
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35 adverse events reported
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