Etrolizumab
Etrolizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target integrin alpha-7.
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Clinical Trials
455 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | 7 | 10 | 12 | 10 | 3 | 39 |
| Asthma | D001249 | EFO_0000270 | J45 | 4 | 14 | 11 | 1 | 2 | 32 |
| Syndrome | D013577 | — | — | 11 | 16 | 3 | 1 | 4 | 30 |
| Pneumonia | D011014 | EFO_0003106 | J18 | 2 | 3 | 20 | 3 | 2 | 28 |
| Communicable diseases | D003141 | — | — | 3 | 7 | 10 | 6 | 2 | 26 |
| Healthy volunteers/patients | — | — | — | 13 | 2 | — | 1 | 2 | 17 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 2 | 5 | 2 | 5 | — | 14 |
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | 2 | — | 2 | 3 | 4 | 11 |
| Obstructive lung diseases | D008173 | — | — | 1 | 5 | 2 | 3 | — | 11 |
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | 3 | 6 | 2 | 1 | 11 |
Show 88 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 34 | 53 | 22 | — | 1 | 91 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 30 | 38 | 4 | — | 1 | 56 |
| Myeloid leukemia | D007951 | — | C92 | 30 | 37 | 4 | — | 1 | 55 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 15 | 27 | 15 | — | — | 49 |
| Lymphoid leukemia | D007945 | — | C91 | 12 | 19 | 15 | — | — | 40 |
| Lymphoma | D008223 | — | C85.9 | 12 | 18 | 7 | — | — | 31 |
| Myelodysplastic syndromes | D009190 | — | D46 | 14 | 20 | 2 | — | 1 | 30 |
| Recurrence | D012008 | — | — | 17 | 15 | 1 | — | — | 25 |
| Preleukemia | D011289 | — | — | 11 | 15 | 2 | — | 1 | 24 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 10 | 11 | 3 | — | — | 19 |
Show 82 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 9 | 8 | — | — | 2 | 17 |
| Multiple myeloma | D009101 | — | C90.0 | 5 | 6 | — | — | — | 10 |
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | 5 | 7 | — | — | — | 10 |
| Hematologic neoplasms | D019337 | — | — | 2 | 6 | — | — | 1 | 8 |
| Plasma cell neoplasms | D054219 | — | — | 5 | 4 | — | — | — | 8 |
| Myelomonocytic leukemia juvenile | D054429 | — | C93.3 | 6 | 5 | — | — | 1 | 8 |
| Mantle-cell lymphoma | D020522 | — | C83.1 | 4 | 7 | — | — | — | 8 |
| Carcinoma | D002277 | — | C80.0 | 4 | 4 | — | — | 1 | 7 |
| Myelomonocytic leukemia chronic | D015477 | — | C93.1 | 5 | 4 | — | — | 1 | 7 |
| Refractory anemia with excess of blasts | D000754 | — | D46.2 | 1 | 6 | — | — | — | 6 |
Show 146 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 3 | — | — | — | — | 3 |
| Primary myelofibrosis | D055728 | — | D47.4 | 2 | — | — | — | — | 2 |
| Adenocarcinoma | D000230 | — | — | 2 | — | — | — | — | 2 |
| Adrenal gland neoplasms | D000310 | EFO_0003850 | C74 | 1 | — | — | — | 1 | 2 |
| Pharmacokinetics | D010599 | — | — | 1 | — | — | — | 1 | 2 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | 1 | — | — | — | 1 | 2 |
| Castration-resistant prostatic neoplasms | D064129 | — | — | 1 | — | — | — | — | 1 |
| Leukemia myeloid chronic atypical bcr-abl negative | D054438 | — | C92.2 | 1 | — | — | — | — | 1 |
| Thrombocytosis | D013922 | — | D75.83 | 1 | — | — | — | — | 1 |
| Malaria | D008288 | EFO_0001068 | B54 | 1 | — | — | — | — | 1 |
Show 26 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carpal tunnel syndrome | D002349 | EFO_0004143 | G56.0 | — | — | — | — | 2 | 2 |
| Anesthesia | D000758 | — | — | — | — | — | — | 2 | 2 |
| Adrenocortical adenoma | D018246 | — | — | — | — | — | — | 1 | 1 |
| Cytokine release syndrome | D000080424 | — | D89.83 | — | — | — | — | 1 | 1 |
| Viral pneumonia | D011024 | EFO_0007541 | J12.9 | — | — | — | — | 1 | 1 |
| Papilloma | D010212 | — | — | — | — | — | — | 1 | 1 |
| Snoring | D012913 | — | R06.83 | — | — | — | — | 1 | 1 |
| Erectile dysfunction | D007172 | EFO_0004234 | F52.21 | — | — | — | — | 1 | 1 |
| Drug monitoring | D016903 | — | — | — | — | — | — | 1 | 1 |
| Depression | D003863 | — | F33.9 | — | — | — | — | 1 | 1 |
Show 27 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Etrolizumab |
| INN | etrolizumab |
| Description | Etrolizumab (humanized mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL1743015 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | I2A72G2V3J (ChemIDplus, GSRS) |
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