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Drug ReportsEtrolizumab
Etrolizumab
Etrolizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target integrin alpha-7.
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
433 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AsthmaD001249EFO_0000270J45214111230
Healthy volunteers/patients———122—1216
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.92524—13
PneumoniaD011014EFO_0003106—1292—12
Urinary tract infectionsD014552EFO_0003103N39.0—362111
Atrial fibrillationD001281EFO_0000275I48.01—2249
Bacterial infectionsD001424—A49522119
InfectionsD007239EFO_0000544—312319
HypertensionD006973EFO_0000537I102——114
Respiratory tract infectionsD012141—J06.9—11114
Show 43 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Myeloid leukemia acuteD015470—C92.027345—152
Precursor cell lymphoblastic leukemia-lymphomaD054198—C91.0142414——45
Myelodysplastic syndromesD009190—D4613172—126
Hodgkin diseaseD006689—C81561——10
Ulcerative colitisD003093EFO_0000729K51226——10
B-cell chronic lymphocytic leukemiaD015451—C91.1521——7
MelanomaD008545——241——6
Large b-cell lymphoma diffuseD016403—C83.3331——6
Ventilator-associated pneumoniaD053717EFO_1001865J95.851——5—16
Multiple sclerosisD009103EFO_0003885G35—42——6
Show 50 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-hodgkin lymphomaD008228—C85.998———13
Multiple myelomaD009101—C90.056———10
Mantle-cell lymphomaD020522—C83.147———8
Bcr-abl positive chronic myelogenous leukemiaD015464EFO_0000340—36———7
Myelomonocytic leukemia chronicD015477—C93.154——17
Myeloid leukemia chronic-phaseD015466——32———5
NeoplasmsD009369—C8042———5
Biphenotypic leukemia acuteD015456—C95.013———4
Colorectal neoplasmsD015179——13———3
Type 1 diabetes mellitusD003922EFO_0001359E1012——13
Show 94 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Primary myelofibrosisD055728—D47.42————2
PharmacokineticsD010599——1———12
Type 2 diabetes mellitusD003924EFO_0001360E112————2
Hematologic neoplasmsD019337——1————1
Castration-resistant prostatic neoplasmsD064129——1————1
Leukemia myeloid chronic atypical bcr-abl negativeD054438—C92.21————1
ThrombocytosisD013922HP_0001894D75.831————1
MalariaD008288EFO_0001068B541————1
Aplastic anemiaD000741HP_0001915D61.91————1
Jaw fracturesD007572——1————1
Show 13 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Carpal tunnel syndromeD002349EFO_0004143G56.0————22
AnesthesiaD000758——————22
Cytokine release syndromeD000080424—D89.83————11
Viral pneumoniaD011024EFO_0007541J12.9————11
SnoringD012913—R06.83————11
Lung diseasesD008171HP_0002088J98.4————11
Erectile dysfunctionD007172EFO_0004234F52.21————11
Drug monitoringD016903——————11
Bipolar disorderD001714EFO_0000289F30.9————11
Polycystic ovary syndromeD011085EFO_0000660E28.2————11
Show 18 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameEtrolizumab
INNetrolizumab
Description
Etrolizumab (humanized mab)
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL1743015
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDI2A72G2V3J (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
ITGA7
ITGA7
Organism
Homo sapiens
Gene name
ITGA7
Gene synonyms
NCBI Gene ID
Protein name
integrin alpha-7
Protein synonyms
integrin alpha 7 chain
Uniprot ID
Mouse ortholog
Itga7 (16404)
integrin alpha-7 (Q61738)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 482 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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9 adverse events reported
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