Etoricoxib
Etoricoxib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against prostaglandin G/H synthase 2.
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Clinical
Clinical Trials
122 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Postoperative pain | D010149 | — | G89.18 | — | 2 | 1 | 2 | — | 5 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | 3 | — | 1 | — | 4 |
| Pain | D010146 | EFO_0003843 | R52 | — | 1 | — | 2 | — | 3 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | 2 | — | 1 | — | 3 |
| Sprains and strains | D013180 | — | — | — | — | — | 2 | — | 2 |
| Neuralgia | D009437 | EFO_0009430 | — | — | — | — | 1 | — | 1 |
| Postherpetic neuralgia | D051474 | — | — | — | — | — | 1 | — | 1 |
| Tendinopathy | D052256 | EFO_1001434 | M77.9 | — | — | — | 1 | — | 1 |
| Hyperalgesia | D006930 | — | — | — | — | — | 1 | — | 1 |
| Appendicitis | D001064 | EFO_0007149 | K37 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hip osteoarthritis | D015207 | EFO_1000786 | M16 | — | 1 | 1 | — | — | 2 |
| Low back pain | D017116 | — | M54.5 | — | — | 1 | — | — | 1 |
| Back pain | D001416 | — | M54 | — | — | 1 | — | — | 1 |
| Hysterectomy | D007044 | EFO_0003881 | — | — | — | 1 | — | — | 1 |
| Ovariectomy | D010052 | — | — | — | — | 1 | — | — | 1 |
| Salpingectomy | D058994 | — | — | — | — | 1 | — | — | 1 |
| Surgical blood loss | D016063 | — | — | — | — | 1 | — | — | 1 |
| Replacement arthroplasty hip | D019644 | — | — | — | — | 1 | — | — | 1 |
| Rheumatic diseases | D012216 | — | M79.0 | — | — | 1 | — | — | 1 |
| Bursitis | D002062 | EFO_1000941 | M71.9 | — | — | 1 | — | — | 1 |
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Indications Phases 2
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Indications Phases 1
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Etoricoxib |
| INN | etoricoxib |
| Description | Etoricoxib is a member of the class of bipyridines that is 2,3'-bipyridine which is substituted at the 3, 5, and 6' positions by 4-(methylsulfonyl)phenyl, chlorine, and methyl groups, respectively. It has a role as a cyclooxygenase 2 inhibitor and a non-steroidal anti-inflammatory drug. It is a sulfone, a member of bipyridines and an organochlorine compound. |
| Classification | Small molecule |
| Drug class | cyclooxygenase-2 inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1ccc(-c2ncc(Cl)cc2-c2ccc(S(C)(=O)=O)cc2)cn1 |
Identifiers
| PDB | — |
| CAS-ID | 202409-33-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL416146 |
| ChEBI ID | 6339 |
| PubChem CID | 123619 |
| DrugBank | DB01628 |
| UNII ID | WRX4NFY03R (ChemIDplus, GSRS) |
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Etoricoxib – Organon
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Safety
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Adverse Events
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2,378 adverse events reported
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