Etoricoxib
Etoricoxib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against prostaglandin G/H synthase 2.
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Clinical Trials
119 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | 1 | 5 | 8 | 3 | 8 | 24 |
| Postoperative pain | D010149 | — | G89.18 | — | 3 | 6 | 9 | 3 | 21 |
| Pain | D010146 | EFO_0003843 | R52 | 1 | 1 | — | 6 | 4 | 12 |
| Back pain | D001416 | HP_0003418 | M54 | — | — | 5 | 3 | 1 | 9 |
| Arthritis | D001168 | HP_0001369 | M05-M14 | — | 2 | 3 | 2 | 2 | 9 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | 2 | 1 | 2 | 3 | 8 |
| Low back pain | D017116 | HP_0003419 | M54.5 | — | — | 5 | 2 | 1 | 8 |
| Spondylarthritis | D025241 | — | — | — | 1 | 2 | 1 | 4 | 8 |
| Spondylitis | D013166 | — | M46.9 | — | 1 | 2 | 1 | 3 | 7 |
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | 1 | 3 | 2 | 1 | 7 |
Show 29 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ankylosing spondylitis | D013167 | EFO_0003898 | M45 | — | 1 | 2 | — | 3 | 6 |
| Hip osteoarthritis | D015207 | EFO_1000786 | M16 | — | 1 | 1 | — | — | 2 |
| Anterior cruciate ligament injuries | D000070598 | — | — | — | — | 1 | — | — | 1 |
| Brachial plexus block | D065527 | — | — | — | — | 1 | — | — | 1 |
| Radius fractures | D011885 | EFO_0003957 | — | — | — | 1 | — | — | 1 |
| Wrist fractures | D000092503 | — | — | — | — | 1 | — | — | 1 |
| Pain management | D059408 | — | — | — | 1 | 1 | — | — | 1 |
| Toothache | D014098 | — | K08.89 | — | — | 1 | — | — | 1 |
| Hysterectomy | D007044 | EFO_0003881 | — | — | — | 1 | — | — | 1 |
| Ovariectomy | D010052 | — | — | — | — | 1 | — | — | 1 |
Show 10 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Necrosis | D009336 | — | — | — | 1 | — | — | — | 1 |
| Syndrome | D013577 | — | — | — | 1 | — | — | — | 1 |
| Acrodynia | D000170 | EFO_1001756 | — | — | 1 | — | — | — | 1 |
| Somatoform disorders | D013001 | — | F45 | — | 1 | — | — | — | 1 |
| Prostatic neoplasms | D011471 | — | C61 | — | 1 | — | — | — | 1 |
| Melanoma | D008545 | — | — | 1 | 1 | — | — | — | 1 |
| Spine osteoarthritis | D055013 | EFO_1000787 | — | 1 | 1 | — | — | — | 1 |
| Hiv | D006678 | — | — | — | 1 | — | — | — | 1 |
| Polyneuropathies | D011115 | EFO_0009562 | A69.22 | — | 1 | — | — | — | 1 |
| Radiculopathy | D011843 | — | M54.1 | — | 1 | — | — | — | 1 |
Show 4 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 4 | — | — | — | 1 | 5 |
| Therapeutic equivalency | D013810 | — | — | 2 | — | — | — | — | 2 |
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | 1 | — | — | — | — | 1 |
| Inflammation | D007249 | MP_0001845 | — | 1 | — | — | — | — | 1 |
| Myalgia | D063806 | HP_0003326 | M79.1 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Laparoscopy | D010535 | — | — | — | — | — | — | 1 | 1 |
| Edema | D004487 | HP_0000969 | R60.9 | — | — | — | — | 1 | 1 |
| Trismus | D014313 | — | — | — | — | — | — | 1 | 1 |
| Uterine hemorrhage | D014592 | — | — | — | — | — | — | 1 | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | — | — | 1 | 1 |
| Male breast neoplasms | D018567 | — | — | — | — | — | — | 1 | 1 |
| Anesthesia | D000758 | — | — | — | — | — | — | 1 | 1 |
| Conduction anesthesia | D000765 | — | — | — | — | — | — | 1 | 1 |
| Dentin sensitivity | D003807 | — | — | — | — | — | — | 1 | 1 |
| Spondylosis | D055009 | — | M47 | — | — | — | — | 1 | 1 |
Show 7 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Etoricoxib |
| INN | etoricoxib |
| Description | Etoricoxib is a member of the class of bipyridines that is 2,3'-bipyridine which is substituted at the 3, 5, and 6' positions by 4-(methylsulfonyl)phenyl, chlorine, and methyl groups, respectively. It has a role as a cyclooxygenase 2 inhibitor and a non-steroidal anti-inflammatory drug. It is a sulfone, a member of bipyridines and an organochlorine compound. |
| Classification | Small molecule |
| Drug class | cyclooxygenase-2 inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1ccc(-c2ncc(Cl)cc2-c2ccc(S(C)(=O)=O)cc2)cn1 |
Identifiers
| PDB | — |
| CAS-ID | 202409-33-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL416146 |
| ChEBI ID | 6339 |
| PubChem CID | 123619 |
| DrugBank | DB01628 |
| UNII ID | WRX4NFY03R (ChemIDplus, GSRS) |
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Etoricoxib – Organon
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Trends
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Safety
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Adverse Events
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2,231 adverse events reported
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