Therapeutic Area | MeSH |
---|---|
nervous system diseases | D009422 |
mental disorders | D001523 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
LUNESTA | Waylis Therapeutics | N-021476 RX | 2004-12-15 | 3 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
eszopiclone | ANDA | 2024-12-31 |
lunesta | New Drug Application | 2025-01-08 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
sleep initiation and maintenance disorders | — | D007319 | F51.01 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sleep initiation and maintenance disorders | D007319 | — | F51.01 | 2 | 2 | 16 | 18 | 11 | 47 |
Obstructive sleep apnea | D020181 | EFO_0003918 | G47.33 | 2 | 6 | — | 3 | 2 | 12 |
Sleep apnea syndromes | D012891 | HP_0010535 | G47.3 | 1 | 5 | — | 3 | 2 | 11 |
Apnea | D001049 | HP_0002104 | R06.81 | 1 | 3 | — | 2 | 1 | 7 |
Depressive disorder | D003866 | EFO_1002014 | F32.A | — | — | 2 | 4 | — | 6 |
Depression | D003863 | — | F33.9 | — | — | 2 | 3 | — | 5 |
Healthy volunteers/patients | — | — | — | 2 | — | 1 | 1 | — | 4 |
Major depressive disorder | D003865 | EFO_0003761 | F22 | — | — | 2 | 2 | — | 4 |
Sleep wake disorders | D012893 | — | G47 | — | 1 | — | 1 | 2 | 4 |
Parasomnias | D020447 | — | G47.5 | — | — | — | 3 | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hyperkinesis | D006948 | HP_0000752 | — | — | — | 2 | — | — | 2 |
Attention deficit disorder with hyperactivity | D001289 | EFO_0003888 | F90 | — | — | 2 | — | — | 2 |
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | — | 1 | — | — | 1 |
Arthritis | D001168 | HP_0001369 | M05-M14 | — | — | 1 | — | — | 1 |
Parkinson disease | D010300 | EFO_0002508 | G20 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Prediabetic state | D011236 | EFO_1001121 | R73.03 | 1 | — | — | — | — | 1 |
Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | 1 | — | — | — | — | 1 |
Glucose intolerance | D018149 | HP_0000833 | R73.03 | 1 | — | — | — | — | 1 |
Malnutrition | D044342 | EFO_0008572 | E40-E46 | 1 | — | — | — | — | 1 |
Marijuana abuse | D002189 | EFO_0007191 | F12 | 1 | — | — | — | — | 1 |
Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Schizophrenia | D012559 | EFO_0000692 | F20 | — | — | — | — | 3 | 3 |
Circadian rhythm sleep disorders | D020178 | — | G47.2 | — | — | — | — | 1 | 1 |
Psychotic disorders | D011618 | — | F20.81 | — | — | — | — | 1 | 1 |
Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | — | — | — | 1 | 1 |
Fatigue | D005221 | HP_0012378 | R53.83 | — | — | — | — | 1 | 1 |
Relapsing-remitting multiple sclerosis | D020529 | EFO_0003929 | — | — | — | — | — | 1 | 1 |
Sclerosis | D012598 | — | — | — | — | — | — | 1 | 1 |
Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | — | — | — | 1 | 1 |
Menopause | D008593 | EFO_0003922 | N95 | — | — | — | — | 1 | 1 |
Inappropriate prescribing | D057970 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Eszopiclone |
INN | eszopiclone |
Description | Eszopiclone is the (5S)- (active) enantiomer of zopiclone. Unlike almost all other hypnotic sedatives, which are approved only for the relief of short-term (6-8 weeks) insomnia, eszopiclone is approved by the U.S. Food and Drug Administration for long-term use. It has a role as a sedative and a central nervous system depressant. It is an enantiomer of a (5R)-zopiclone. |
Classification | Small molecule |
Drug class | hypnotics/tranquilizers (zopiclone type) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CN1CCN(C(=O)O[C@H]2c3nccnc3C(=O)N2c2ccc(Cl)cn2)CC1 |
PDB | — |
CAS-ID | 138729-47-2 |
RxCUI | — |
ChEMBL ID | CHEMBL1522 |
ChEBI ID | 53760 |
PubChem CID | 969472 |
DrugBank | DB00402 |
UNII ID | UZX80K71OE (ChemIDplus, GSRS) |