Estropipate
Ogen (estropipate) is a small molecule pharmaceutical. Estropipate was first approved as Ogen 5 on 1982-01-01. It is used to treat hot flashes, hypogonadism, menopause, menorrhagia, and premature menopause amongst others in the USA.
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Commercial
Trade Name
FDA
EMA
Ogen (discontinued: Estropipate, Ogen, Ortho-est)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| estropipate | ANDA | 2012-03-14 |
Indications
FDA
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Agency Specific
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Clinical
Clinical Trials
239 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pituitary diseases | D010900 | — | E23.7 | — | — | 1 | — | — | 1 |
| Healthy volunteers/patients | — | — | — | — | — | 1 | — | — | 1 |
| Pelvic pain | D017699 | — | — | — | — | 1 | — | — | 1 |
| Dysmenorrhea | D004412 | — | N94.6 | — | — | 1 | — | — | 1 |
| Contraception | D003267 | — | — | — | — | 1 | — | — | 1 |
| Metabolic bone diseases | D001851 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bone density | D015519 | EFO_0003923 | M85 | — | 1 | — | — | — | 1 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | 1 | — | — | — | 1 |
| Metrorrhagia | D008796 | — | N92.1 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Estropipate |
| INN | — |
| Description | Estropipate is a steroid sulfate and a piperazinium salt. It is functionally related to an estrone. |
| Classification | Small molecule |
| Drug class | estrogens; atropine derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C1CNCCN1.C[C@]12CC[C@@H]3c4ccc(OS(=O)(=O)O)cc4CC[C@H]3[C@@H]1CCC2=O |
Identifiers
| PDB | — |
| CAS-ID | 7280-37-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1200980 |
| ChEBI ID | — |
| PubChem CID | 5284555 |
| DrugBank | DB04574 |
| UNII ID | — |
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Estropipate
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Additional graphs summarizing 105 documents
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Safety
Black-box Warning
Black-box warning for: Estropipate
Adverse Events
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731 adverse events reported
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