Eribaxaban
Eribaxaban is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against coagulation factor X.
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Commercial
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Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Thyroid neoplasms | D013964 | EFO_0003841 | — | 1 | 1 | — | — | — | 1 |
| Sarcoma | D012509 | — | — | 1 | 1 | — | — | — | 1 |
| Fibrosarcoma | D005354 | — | — | 1 | 1 | — | — | — | 1 |
| Papillary thyroid cancer | D000077273 | — | — | 1 | 1 | — | — | — | 1 |
| Thyroid diseases | D013959 | HP_0000820 | E00-E07 | 1 | 1 | — | — | — | 1 |
| Myofibromatosis | D018224 | — | — | 1 | 1 | — | — | — | 1 |
Indications Phases 1
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Eribaxaban |
| INN | eribaxaban |
| Description | Eribaxaban is a member of the class of pyrrolidines that is (2R,4R)-N(1)-(p-chlorophenyl)-4-methoxypyrrolidine-1,2-dicarboxamide in which the nitrogen of the 2-carbamoyl group has been substituted by a 2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl group. It is a synthetic organic anticoagulant compound that targets activated factor Xa in the coagulation cascade. It has a role as an anticoagulant, an EC 3.4.21.6 (coagulation factor Xa) inhibitor and a serine protease inhibitor. It is a pyridone, a secondary carboxamide, a member of ureas, a member of monochlorobenzenes, a member of pyrrolidines and a member of monofluorobenzenes. |
| Classification | Small molecule |
| Drug class | antithrombotics, blood coagulation factor XA inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CO[C@@H]1C[C@H](C(=O)Nc2ccc(-n3ccccc3=O)cc2F)N(C(=O)Nc2ccc(Cl)cc2)C1 |
Identifiers
| PDB | — |
| CAS-ID | 536748-46-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL476186 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB06920 |
| UNII ID | 5FCH6YDY7Z (ChemIDplus, GSRS) |
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Safety
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32 adverse events reported
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