Ergocalciferol
Berocca Pn, Drisdol, Ergocalciferol, M.v.c. 9+, M.v.i, M.v.i. Lyophilized, Mvc, Vitamin D, Vitaped (ergocalciferol) is a small molecule pharmaceutical. Ergocalciferol was first approved as Drisdol on 1982-01-01. It is used to treat hypoparathyroidism, hypophosphatemia, and rickets in the USA.
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Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Drisdol (generic drugs available since 1982-01-01, discontinued: Deltalin, Vitamin d)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Phytonadione
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine
+
Riboflavin 5'-phosphate sodium
+
Thiamine
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
+
Vitamin k
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a palmitate
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pantothenic acid
+
Phytonadione
+
Pyridoxine
+
Riboflavin
+
Thiamine
+
Vitamin a palmitate
+
Vitamin e
Ergocalciferol
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| DRISDOL | SS PHARMA | N-003444 RX | 1982-01-01 | 1 products, RLD |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 3 pack family dollar instant hand sanitizers | OTC monograph not final | 2014-11-28 |
| a and d | OTC monograph final | 2020-01-07 |
| a and d plus e | OTC monograph final | 2020-11-06 |
| adult infuvite multiple vitamins | New Drug Application | 2019-05-14 |
| adult infuvite multiple vitamins for infusion pharmacy bulk | New Drug Application | 2013-01-01 |
| ag international | OTC monograph final | 2019-07-23 |
| ameriderm | OTC monograph final | 2022-01-13 |
| animi-3 with vitamin d | unapproved drug other | 2011-05-23 |
| anubis barcelona | OTC monograph final | 2023-09-01 |
| apcal | OTC monograph final | 2013-02-21 |
Show 129 more
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| hypoparathyroidism | — | D007011 | E20 |
| hypophosphatemia | HP_0002148 | D017674 | — |
| rickets | EFO_0005583 | D012279 | E55.0 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
3512 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Vitamin d deficiency | D014808 | EFO_0003762 | E55 | 42 | 70 | 57 | 85 | 397 | 627 |
| Osteoporosis | D010024 | HP_0000939 | M81.0 | 13 | 26 | 45 | 32 | 73 | 184 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 2 | 9 | 6 | 12 | 72 | 101 |
| Chronic renal insufficiency | D051436 | — | N18 | 7 | 16 | 16 | 28 | 31 | 93 |
| Covid-19 | D000086382 | — | U07.1 | 8 | 12 | 16 | 6 | 53 | 91 |
| Healthy volunteers/patients | — | — | — | 26 | 4 | 3 | 2 | 45 | 79 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 4 | 13 | 10 | 11 | 37 | 71 |
| Metabolic bone diseases | D001851 | HP_0000938 | — | 3 | 7 | 6 | 12 | 32 | 58 |
| Secondary hyperparathyroidism | D006962 | EFO_1001173 | — | 3 | 8 | 10 | 22 | 16 | 57 |
| Postmenopausal osteoporosis | D015663 | EFO_0003854 | — | 2 | 4 | 11 | 17 | 21 | 55 |
Show 203 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 14 | 20 | 13 | — | 13 | 54 |
| Colorectal neoplasms | D015179 | — | — | 10 | 25 | 13 | — | 10 | 48 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | 3 | 1 | 4 | — | 22 | 30 |
| Aging | D000375 | GO_0007568 | R41.81 | 2 | 4 | 2 | — | 19 | 26 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 2 | 10 | 5 | — | 5 | 20 |
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | — | 5 | 5 | — | 10 | 19 |
| Inflammatory bowel diseases | D015212 | EFO_0003767 | — | 3 | 2 | 2 | — | 12 | 18 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 6 | 9 | 2 | — | 2 | 16 |
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | 3 | 2 | 1 | — | 11 | 16 |
| Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | 2 | 5 | 3 | — | 8 | 15 |
Show 135 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | 1 | — | — | 9 | 10 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 6 | 2 | — | — | 1 | 9 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | 1 | — | — | 6 | 7 |
| Bone density | D015519 | EFO_0003923 | M85 | — | 1 | — | — | 6 | 7 |
| Exercise | D015444 | EFO_0000483 | — | — | 1 | — | — | 6 | 7 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | 3 | — | — | 3 | 7 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 4 | 1 | — | — | — | 5 |
| Acute kidney injury | D058186 | HP_0001919 | N17 | — | 1 | — | — | 4 | 5 |
| Nutrition disorders | D009748 | EFO_0001069 | — | — | 1 | — | — | 4 | 5 |
| Stress fractures | D015775 | — | M84.3 | — | 1 | — | — | 4 | 5 |
Show 138 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypercholesterolemia | D006937 | HP_0003124 | — | 1 | — | — | — | 7 | 8 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | 1 | — | — | — | 6 | 7 |
| Nutritional status | D009752 | — | — | 1 | — | — | — | 5 | 6 |
| Periodontal diseases | D010510 | — | K05.6 | 1 | — | — | — | 4 | 5 |
| Thyroid diseases | D013959 | HP_0000820 | E00-E07 | 1 | — | — | — | 4 | 5 |
| Muscle strength | D053580 | — | — | 1 | — | — | — | 3 | 4 |
| Diet therapy | D004035 | — | — | 1 | — | — | — | 3 | 4 |
| Morbid obesity | D009767 | EFO_0001074 | — | 1 | — | — | — | 3 | 4 |
| Birth weight | D001724 | EFO_0004344 | — | 1 | — | — | — | 3 | 4 |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | 2 | — | — | — | 2 | 4 |
Show 40 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Weight loss | D015431 | HP_0001824 | — | — | — | — | — | 7 | 7 |
| Cerebral palsy | D002547 | — | G80 | — | — | — | — | 7 | 7 |
| Body composition | D001823 | — | — | — | — | — | — | 5 | 5 |
| Heart disease risk factors | D000082742 | — | — | — | — | — | — | 5 | 5 |
| Body weight changes | D001836 | — | — | — | — | — | — | 5 | 5 |
| Wounds and injuries | D014947 | — | T14.8 | — | — | — | — | 5 | 5 |
| Premenstrual syndrome | D011293 | — | N94.3 | — | — | — | — | 5 | 5 |
| Child development | D002657 | — | — | — | — | — | — | 4 | 4 |
| Fertilization in vitro | D005307 | — | — | — | — | — | — | 4 | 4 |
| Eczema | D004485 | HP_0000964 | L30.9 | — | — | — | — | 4 | 4 |
Show 300 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Ergocalciferol |
| INN | ergocalciferol |
| Description | Vitamin D2 is a vitamin D supplement and has been isolated from alfalfa. It has a role as a nutraceutical, a bone density conservation agent, a rodenticide and a plant metabolite. It is a seco-ergostane, a hydroxy seco-steroid and a vitamin D. |
| Classification | Small molecule |
| Drug class | vitamin D analogs |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@@]2(C)[C@H]1CC[C@@H]2[C@H](C)/C=C/[C@H](C)C(C)C |
Identifiers
| PDB | — |
| CAS-ID | 50-14-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1536 |
| ChEBI ID | 28934 |
| PubChem CID | 5280793 |
| DrugBank | DB00153 |
| UNII ID | VS041H42XC (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Estimated US medical usage
Ergocalciferol
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Trends
PubMed Central
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Additional graphs summarizing 427,690 documents
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Safety
Black-box Warning
Black-box warning for: Citranatal 90 dha, Citranatal assure, Citranatal dha, Citranatal essence, Citranatal rx, Neonatal complete, Neonatal dha, Nestabs, Nestabs dha, Nestabs one, Omega-3 well pack, Pnv prenatal plus multivitamin, Pnv prenatal vitamin, Pnv-select, Pre-tabs dha, Select ob, Select-ob plus dha, Vitafol, Vitafol ob, Vitafol-ob plus dha
Adverse Events
Top Adverse Reactions
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12,237 adverse events reported
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