Ergocalciferol
Berocca Pn, Drisdol, Ergocalciferol, M.v.c. 9+, M.v.i, M.v.i. Lyophilized, Mvc, Vitamin D, Vitaped (ergocalciferol) is a small molecule pharmaceutical. Ergocalciferol was first approved as Drisdol on 1982-01-01. It is used to treat hypoparathyroidism, hypophosphatemia, and rickets in the USA.
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Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Drisdol, Ergocalciferol, Vitamin d (discontinued: Deltalin, Ergocalciferol, Vitamin d)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a palmitate
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Phytonadione
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
+
Vitamin k
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pantothenic acid
+
Phytonadione
+
Pyridoxine
+
Riboflavin
+
Thiamine
+
Vitamin a palmitate
+
Vitamin e
Ergocalciferol
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| DRISDOL | Validus Pharmaceuticals | N-003444 RX | 1982-01-01 | 1 products, RLD |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 3 pack family dollar instant hand sanitizers | OTC monograph not final | 2014-11-28 |
| a and d | OTC monograph final | 2020-01-07 |
| a and d plus e | C200263 | 2025-05-21 |
| adult infuvite multiple vitamins | New Drug Application | 2019-05-14 |
| ag international | OTC monograph final | 2019-07-23 |
| allevia | unapproved drug other | 2025-02-27 |
| ameriderm | C200263 | 2025-06-06 |
| animi-3 with vitamin d | unapproved drug other | 2011-05-23 |
| anubis barcelona | OTC monograph final | 2023-09-01 |
| apcal | OTC monograph final | 2013-02-21 |
Show 122 more
Indications
FDA
EMA
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Agency Specific
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Patent Expiration
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Clinical
Clinical Trials
3747 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Vitamin d deficiency | D014808 | EFO_0003762 | E55 | 50 | 79 | 75 | 100 | 518 | 798 |
| Osteoporosis | D010024 | EFO_0003882 | M81.0 | 15 | 32 | 61 | 51 | 112 | 266 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | 9 | 28 | 21 | 38 | 56 | 143 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 11 | 30 | 21 | 17 | 61 | 129 |
| Chronic renal insufficiency | D051436 | — | N18 | 8 | 21 | 20 | 34 | 43 | 118 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 2 | 10 | 7 | 13 | 83 | 115 |
| Covid-19 | D000086382 | — | U07.1 | 8 | 15 | 18 | 9 | 60 | 106 |
| Healthy volunteers/patients | — | — | — | 27 | 4 | 3 | 2 | 56 | 91 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 4 | 13 | 11 | 14 | 47 | 85 |
| Metabolic bone diseases | D001851 | — | — | 3 | 11 | 7 | 14 | 52 | 84 |
Show 314 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 11 | 29 | 15 | — | 12 | 57 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | 4 | 1 | 4 | — | 25 | 34 |
| Lymphoma | D008223 | — | C85.9 | 7 | 11 | 9 | — | 5 | 28 |
| Aging | D000375 | GO_0007568 | R41.81 | 2 | 4 | 3 | — | 19 | 27 |
| Adenocarcinoma | D000230 | — | — | 6 | 12 | 4 | — | 2 | 23 |
| Bone density | D015519 | EFO_0003923 | M85 | 1 | 2 | 1 | — | 20 | 23 |
| Cognitive dysfunction | D060825 | — | G31.84 | 2 | 7 | 3 | — | 12 | 21 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 7 | 9 | 2 | — | 3 | 19 |
| Wounds and injuries | D014947 | — | T14.8 | 1 | 5 | 2 | — | 11 | 18 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 2 | 10 | 3 | — | 3 | 17 |
Show 197 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Periodontitis | D010518 | EFO_0000649 | K05.3 | 1 | 2 | — | — | 17 | 20 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 6 | 4 | — | — | 3 | 13 |
| Colitis | D003092 | EFO_0003872 | K52.9 | 2 | 1 | — | — | 10 | 12 |
| Myeloid leukemia | D007951 | — | C92 | 8 | 6 | — | — | — | 11 |
| Ulcer | D014456 | MPATH_579 | — | 2 | 1 | — | — | 8 | 10 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | 1 | — | — | 9 | 10 |
| Thyroid diseases | D013959 | — | E00-E07 | 1 | 1 | — | — | 7 | 9 |
| Exercise | D015444 | EFO_0000483 | — | — | 1 | — | — | 8 | 9 |
| Acute kidney injury | D058186 | — | N17 | 1 | 1 | — | — | 6 | 8 |
| Preleukemia | D011289 | — | — | 5 | 4 | — | — | — | 7 |
Show 210 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Periodontal diseases | D010510 | — | K05.6 | 1 | — | — | — | 7 | 8 |
| Hypercholesterolemia | D006937 | — | — | 1 | — | — | — | 7 | 8 |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | 3 | — | — | — | 3 | 6 |
| Nutritional status | D009752 | — | — | 1 | — | — | — | 5 | 6 |
| Morbid obesity | D009767 | EFO_0001074 | — | 1 | — | — | — | 5 | 6 |
| Gingivitis | D005891 | — | K05.10 | 1 | — | — | — | 5 | 6 |
| Ovarian epithelial carcinoma | D000077216 | — | — | 3 | — | — | — | 2 | 5 |
| Chronic disease | D002908 | — | — | 1 | — | — | — | 4 | 5 |
| Diet therapy | D004035 | — | — | 1 | — | — | — | 3 | 4 |
| Head and neck neoplasms | D006258 | — | — | 2 | — | — | — | 2 | 4 |
Show 51 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Post-acute covid-19 syndrome | D000094024 | — | — | — | — | — | — | 9 | 9 |
| Healthy diet | D000072001 | — | — | — | — | — | — | 9 | 9 |
| Cerebral palsy | D002547 | — | G80 | — | — | — | — | 8 | 8 |
| Back pain | D001416 | — | M54 | — | — | — | — | 7 | 7 |
| Vitamin b 12 deficiency | D014806 | EFO_0000734 | E53.8 | — | — | — | — | 6 | 6 |
| Body composition | D001823 | — | — | — | — | — | — | 6 | 6 |
| Urinary incontinence | D014549 | — | R32 | — | — | — | — | 6 | 6 |
| Premenstrual syndrome | D011293 | — | N94.3 | — | — | — | — | 6 | 6 |
| Folic acid deficiency | D005494 | EFO_0001070 | E53.8 | — | — | — | — | 5 | 5 |
| Heart disease risk factors | D000082742 | — | — | — | — | — | — | 5 | 5 |
Show 434 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Ergocalciferol |
| INN | ergocalciferol |
| Description | Vitamin D2 is a vitamin D supplement and has been isolated from alfalfa. It has a role as a nutraceutical, a bone density conservation agent, a rodenticide and a plant metabolite. It is a seco-ergostane, a hydroxy seco-steroid and a vitamin D. |
| Classification | Small molecule |
| Drug class | vitamin D analogs |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@@]2(C)[C@H]1CC[C@@H]2[C@H](C)/C=C/[C@H](C)C(C)C |
Identifiers
| PDB | — |
| CAS-ID | 50-14-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1536 |
| ChEBI ID | 28934 |
| PubChem CID | 5280793 |
| DrugBank | DB00153 |
| UNII ID | VS041H42XC (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Ergocalciferol
Total medical expenditures per year (USD, in millions)
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Trends
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Additional graphs summarizing 357,769 documents
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Safety
Black-box Warning
Black-box warning for: Citranatal assure, Citranatal essence, Nestabs, Nestabs dha, Nestabs one, Omega-3 well pack, Pnv prenatal plus multivitamin, Pnv prenatal vitamin, Pnv-select, Pre-tabs dha, Select ob, Select-ob plus dha, Vitafol, Vitafol ob, Vitafol-ob plus dha
Adverse Events
Top Adverse Reactions
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25,624 adverse events reported
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