Tradename | Company | Number | Date | Products |
---|---|---|---|---|
REZIPRES | Dr Reddys Laboratories | N-213536 PEND | 2021-06-14 | 3 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
EPHEDRINE SULFATE | Akorn | N-208609 RX | 2017-03-01 | 1 products |
EPHEDRINE SULFATE | Endo | N-213994 RX | 2020-10-16 | 2 products, RLD, RS |
AKOVAZ | Exela Pharma Sciences | N-208289 RX | 2016-04-29 | 2 products, RLD, RS |
EMERPHED | Nexus Biopharma | N-213407 RX | 2020-04-17 | 2 products, RLD, RS |
CORPHEDRA | Par Pharmaceutical | N-208943 RX | 2017-01-27 | 1 products |
Brand Name | Status | Last Update |
---|---|---|
akovaz | New Drug Application | 2020-11-27 |
bronkaid | OTC monograph final | 2020-06-11 |
corphedra | New Drug Application | 2018-10-17 |
emerphed | New Drug Application | 2022-09-30 |
ephed asthma | OTC monograph final | 2019-03-28 |
ephed plus | OTC monograph final | 2019-04-02 |
ephed plus liquid | OTC monograph final | 2019-04-02 |
ephedrine hydrochloride | C200263 | 2023-12-14 |
ephedrine sulfate | ANDA | 2023-10-30 |
primatene | OTC monograph final | 2021-01-25 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
asthma | EFO_0000270 | D001249 | J45 |
bronchial spasm | — | D001986 | — |
orthostatic hypotension | — | D007024 | I95.1 |
rhinitis | EFO_0008521 | D012220 | J31 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypotension | D007022 | EFO_0005251 | I95 | — | 3 | 4 | 8 | 21 | 34 |
Allergic rhinitis | D065631 | — | J30.9 | — | 3 | 1 | 4 | 4 | 12 |
Spinal anesthesia | D000775 | — | — | — | 1 | 1 | 4 | 5 | 11 |
Allergic rhinitis seasonal | D006255 | EFO_0003956 | J30 | 1 | 2 | 3 | 1 | 3 | 10 |
Anesthesia | D000758 | — | — | — | — | 1 | 2 | 7 | 10 |
Common cold | D003139 | EFO_0007214 | J00 | 1 | — | 3 | 2 | — | 6 |
Pre-eclampsia | D011225 | EFO_0000668 | O14 | — | — | 1 | 1 | 4 | 6 |
Cesarean section | D002585 | — | — | — | 1 | — | 2 | 3 | 6 |
Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | — | 4 | 1 | 5 |
Respiratory tract infections | D012141 | — | J06.9 | 1 | — | 2 | 1 | — | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Obesity | D009765 | EFO_0001073 | E66.9 | 1 | 1 | 1 | — | 5 | 8 |
Rhinitis | D012220 | EFO_0008521 | J31 | 1 | — | 4 | — | 1 | 6 |
Cough | D003371 | HP_0012735 | R05 | — | 1 | 2 | — | — | 3 |
Allergic rhinitis perennial | D012221 | EFO_1001417 | J30.89 | — | — | 2 | — | 1 | 3 |
Vasomotor rhinitis | D012223 | EFO_0007533 | J30.0 | — | — | 2 | — | 1 | 3 |
Postoperative nausea and vomiting | D020250 | EFO_0004888 | — | — | — | 1 | — | 1 | 2 |
Inflammation | D007249 | MP_0001845 | — | — | — | 2 | — | — | 2 |
Obstetrical anesthesia | D000773 | — | — | — | 1 | 1 | — | — | 2 |
Analgesia | D000698 | — | — | — | — | 1 | — | 1 | 2 |
Pharyngitis | D010612 | — | R07.0 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hiv infections | D015658 | EFO_0000764 | B20 | — | 1 | — | — | 1 | 2 |
Lacrimal duct obstruction | D007767 | — | — | 1 | 1 | — | — | — | 1 |
Pain | D010146 | EFO_0003843 | R52 | 1 | 1 | — | — | — | 1 |
Congenital myasthenic syndromes | D020294 | Orphanet_590 | G70.2 | 1 | 1 | — | — | — | 1 |
Vomiting | D014839 | HP_0002013 | R11.1 | — | 1 | — | — | — | 1 |
Nausea | D009325 | HP_0002018 | R11.0 | — | 1 | — | — | — | 1 |
Enuresis | D004775 | — | R32 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 15 | — | — | — | 7 | 22 |
Pure autonomic failure | D054970 | — | — | 2 | — | — | — | — | 2 |
Hypersensitivity | D006967 | HP_0012393 | T78.40 | 2 | — | — | — | — | 2 |
Hypertension | D006973 | EFO_0000537 | I10 | 1 | — | — | — | 1 | 2 |
Shy-drager syndrome | D012791 | EFO_1001050 | — | 2 | — | — | — | — | 2 |
Orthostatic hypotension | D007024 | — | I95.1 | 1 | — | — | — | — | 1 |
Fever | D005334 | HP_0001945 | R50.9 | 1 | — | — | — | — | 1 |
Acute pain | D059787 | — | R52 | 1 | — | — | — | — | 1 |
Back pain | D001416 | HP_0003418 | M54 | 1 | — | — | — | — | 1 |
Multiple system atrophy | D019578 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Carotid stenosis | D016893 | — | — | — | — | — | — | 2 | 2 |
Hip fractures | D006620 | EFO_0003964 | S72.00 | — | — | — | — | 2 | 2 |
Nasal obstruction | D015508 | HP_0001742 | — | — | — | — | — | 2 | 2 |
Carotid endarterectomy | D016894 | — | — | — | — | — | — | 2 | 2 |
Hysterectomy | D007044 | EFO_0003881 | — | — | — | — | — | 1 | 1 |
Acute cholecystitis | D041881 | EFO_1001289 | K81.0 | — | — | — | — | 1 | 1 |
Cholecystitis | D002764 | HP_0001082 | K81 | — | — | — | — | 1 | 1 |
Morbid obesity | D009767 | EFO_0001074 | — | — | — | — | — | 1 | 1 |
Compression fractures | D050815 | — | — | — | — | — | — | 1 | 1 |
Male breast neoplasms | D018567 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Ephedrine |
INN | — |
Description | (-)-ephedrine is a phenethylamine alkaloid that is 2-phenylethanamine substituted by a methyl group at the amino nitrogen and a methyl and a hydroxy group at position 2 and 1 respectively. It has a role as a nasal decongestant, a sympathomimetic agent, a vasoconstrictor agent, a xenobiotic, an environmental contaminant, a plant metabolite and a bacterial metabolite. It is a member of phenylethanolamines and a phenethylamine alkaloid. It is a conjugate base of a (-)-ephedrinium. |
Classification | Small molecule |
Drug class | sympathomimetics |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CN[C@@H](C)[C@H](O)c1ccccc1 |
PDB | — |
CAS-ID | 299-42-3 |
RxCUI | — |
ChEMBL ID | CHEMBL211456 |
ChEBI ID | 15407 |
PubChem CID | 9294 |
DrugBank | DB01364 |
UNII ID | — |