Enoxaparin sodium
Enoxaparin, Inhixa, Lovenox (enoxaparin sodium) is an oligosaccharide pharmaceutical. Enoxaparin sodium was first approved as Lovenox (preservative free) on 1993-03-29. It is used to treat myocardial infarction, postoperative complications, pulmonary embolism, thromboembolism, and thrombophlebitis amongst others in the USA. It has been approved in Europe to treat venous thromboembolism. The pharmaceutical is active against antithrombin-III.
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Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Enoxaparin, Lovenox (discontinued: Lovenox)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| enoxaparin sodium | ANDA | 2025-01-09 |
| enoxaparin sodium injection,usp | ANDA | 2024-08-05 |
| enoxiluv kit | unapproved drug other | 2024-10-05 |
| lovenox | New Drug Application | 2024-05-31 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| J1650 | Injection, enoxaparin sodium, 10 mg |
Clinical
No data
Drug
General
| Drug common name | Enoxaparin sodium |
| INN | enoxaparin sodium |
| Description | Enoxaparin sodium, sold under the brand name Lovenox among others, is an anticoagulant medication (blood thinner). It is used to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) including during pregnancy and following certain types of surgery. It is also used in those with acute coronary syndrome (ACS) and heart attacks. It is given by injection just under the skin or into a vein. It is also used during hemodialysis.
|
| Classification | Oligosaccharide |
| Drug class | heparin derivatives and low molecular weight (or depolymerized) heparins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 679809-58-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201476 |
| ChEBI ID | — |
| PubChem CID | 772 |
| DrugBank | DB01225 |
| UNII ID | 8NZ41MIK1O (ChemIDplus, GSRS) |
Target
Agency Approved
SERPINC1
SERPINC1
Organism
Homo sapiens
Gene name
SERPINC1
Gene synonyms
AT3
NCBI Gene ID
Protein name
antithrombin-III
Protein synonyms
serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1, Serpin C1, serpin peptidase inhibitor clade C member 1, serpin peptidase inhibitor, clade C (antithrombin), member 1
Uniprot ID
Mouse ortholog
Serpinc1 (11905)
antithrombin-III (P32261)
Alternate
No data
Variants
No data
Financial
Revenue by drug
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Lovenox – Sanofi
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Estimated US medical usage
Enoxaparin sodium
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Enoxaparin
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Trends
No data
Safety
Black-box Warning
Black-box warning for: Enoxaparin sodium, Enoxaparin sodium injection,usp, Enoxiluv kit, Lovenox
Adverse Events
0 adverse events reported
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