ENFLURANE
Ethrane (enflurane) is a small molecule pharmaceutical. Enflurane was first approved as Ethrane on 1982-01-01. It is used to treat status asthmaticus and ventricular premature complexes in the USA.
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Indications
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Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| status asthmaticus | — | D013224 | — |
| ventricular premature complexes | — | D018879 | I49.3 |
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10 clinical trials
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Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasm micrometastasis | D061206 | — | — | — | 1 | — | — | — | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 1 | — | — | — | 1 |
| Infections | D007239 | EFO_0000544 | — | 1 | 1 | — | — | — | 1 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 1 | 1 | — | — | — | 1 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 1 | 1 | — | — | — | 1 |
| Communicable diseases | D003141 | — | — | 1 | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| General anesthesia | D000768 | — | — | — | — | — | — | 1 | 1 |
| Hemorrhoids | D006484 | EFO_0009552 | K64 | — | — | — | — | 1 | 1 |
| Carcinoma | D002277 | — | C80.0 | — | — | — | — | 1 | 1 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | — | — | — | 1 | 1 |
| Fallopian tube neoplasms | D005185 | — | — | — | — | — | — | 1 | 1 |
| Ovarian epithelial carcinoma | D000077216 | — | — | — | — | — | — | 1 | 1 |
| Refractive errors | D012030 | EFO_0003908 | H52.7 | — | — | — | — | 1 | 1 |
| Myopia | D009216 | EFO_0003927 | H52.1 | — | — | — | — | 1 | 1 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | — | 1 | 1 |
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ENFLURANE |
| INN | enflurane |
| Description | Enflurane is an ether in which the oxygen atom is connected to 2-chloro-1,1,2-trifluoroethyl and difluoromethyl groups. It has a role as an anaesthetic. It is an organofluorine compound, an organochlorine compound and an ether. It is functionally related to a methoxyethane. |
| Classification | Small molecule |
| Drug class | general inhalation anesthetics (halogenated alkane derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | FC(F)OC(F)(F)C(F)Cl |
Identifiers
| PDB | — |
| CAS-ID | 13838-16-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1257 |
| ChEBI ID | 4792 |
| PubChem CID | 3226 |
| DrugBank | DB00228 |
| UNII ID | 91I69L5AY5 (ChemIDplus, GSRS) |
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339 adverse events reported
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