Enbucrilate
Enbucrilate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
76 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Esophageal and gastric varices | D004932 | EFO_0009545 | I85 | — | — | 5 | 1 | 11 | 17 |
| Wounds and injuries | D014947 | — | T14.8 | — | — | — | 1 | 3 | 4 |
| Wound healing | D014945 | GO_0042060 | — | — | — | — | 1 | 2 | 3 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | 1 | 1 | 2 |
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | — | — | — | 1 | — | 1 |
| Digestive system fistula | D016154 | — | — | — | — | — | 1 | — | 1 |
| Oral surgical procedures | D019647 | — | — | — | — | — | 1 | — | 1 |
| Periodontal diseases | D010510 | — | K05.6 | — | — | — | 1 | — | 1 |
| Dental scaling | D012534 | — | — | — | — | — | 1 | — | 1 |
| Tissue adhesives | D014014 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | 2 | — | 2 | 4 |
| Fibrosis | D005355 | — | — | — | — | 1 | — | 2 | 3 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 1 | 1 | — | — | 3 |
| Ulcer | D014456 | MPATH_579 | — | — | — | 1 | — | 1 | 2 |
| Gastrointestinal hemorrhage | D006471 | — | K92.2 | — | — | 1 | — | — | 1 |
| Hypospadias | D007021 | EFO_0004209 | Q54 | — | 1 | 1 | — | — | 1 |
| Episiotomy | D004841 | — | — | — | — | 1 | — | — | 1 |
| Dermatitis | D003872 | — | L30.9 | — | — | 1 | — | — | 1 |
| Contact dermatitis | D003877 | — | L25 | — | — | 1 | — | — | 1 |
| Hepatic insufficiency | D048550 | — | — | — | — | 1 | — | — | 1 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lacerations | D022125 | — | — | — | 1 | — | — | 1 | 2 |
| Pancreatic fistula | D010185 | — | — | 1 | 1 | — | — | — | 2 |
| Pancreaticoduodenectomy | D016577 | — | — | 1 | 1 | — | — | — | 2 |
| Anastomotic leak | D057868 | — | — | 1 | 1 | — | — | — | 2 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Surgical wound | D000072836 | — | — | 2 | — | — | — | 2 | 4 |
| Postoperative pain | D010149 | — | G89.18 | 1 | — | — | — | 1 | 2 |
| Pilonidal sinus | D010864 | — | L05 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hernia | D006547 | — | K40-K46 | — | — | — | — | 11 | 11 |
| Inguinal hernia | D006552 | HP_0000023 | K40 | — | — | — | — | 10 | 10 |
| Gingival recession | D005889 | — | K06.0 | — | — | — | — | 5 | 5 |
| Varicose veins | D014648 | — | I83.90 | — | — | — | — | 4 | 4 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | — | 2 | 2 |
| Wound closure techniques | D058106 | — | — | — | — | — | — | 2 | 2 |
| Subdural hematoma chronic | D020200 | — | — | — | — | — | — | 2 | 2 |
| Ventral hernia | D006555 | EFO_1001866 | K43 | — | — | — | — | 2 | 2 |
| Emergencies | D004630 | — | — | — | — | — | — | 2 | 2 |
| Impacted tooth | D014095 | — | K01.1 | — | — | — | — | 2 | 2 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Enbucrilate |
| INN | enbucrilate |
| Description | Enbucrilate is a nitrile and an alpha,beta-unsaturated monocarboxylic acid. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C=C(C#N)C(=O)OCCCC |
Identifiers
| PDB | — |
| CAS-ID | 6606-65-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2104251 |
| ChEBI ID | — |
| PubChem CID | 23087 |
| DrugBank | — |
| UNII ID | F8CEP82QNP (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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99 adverse events reported
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