Emvododstat
Emvododstat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target dihydroorotate dehydrogenase (quinone), mitochondrial.
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Commercial
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Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | — | — | 1 | 1 | — | — | 1 |
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | — | 1 | 1 | — | — | 1 |
| Coronavirus | D017934 | — | — | — | 1 | 1 | — | — | 1 |
| Pneumonia | D011014 | EFO_0003106 | — | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sarcoma | D012509 | — | — | 1 | 1 | — | — | — | 1 |
| Kaposi sarcoma | D012514 | — | C46 | 1 | 1 | — | — | — | 1 |
| Neurofibromatosis 2 | D016518 | — | Q85.02 | — | 1 | — | — | — | 1 |
| Neurofibromatosis 1 | D009456 | — | Q85.01 | — | 1 | — | — | — | 1 |
| Neurofibromatoses | D017253 | — | Q85.00 | — | 1 | — | — | — | 1 |
| Neurofibroma | D009455 | EFO_0000622 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 1 | — | — | — | — | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | — | — | — | 1 |
| Central nervous system neoplasms | D016543 | — | — | 1 | — | — | — | — | 1 |
| Nervous system neoplasms | D009423 | — | — | 1 | — | — | — | — | 1 |
| Leukemia | D007938 | — | C95 | 1 | — | — | — | — | 1 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 1 | — | — | — | — | 1 |
| Myeloid leukemia | D007951 | — | C92 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Emvododstat |
| INN | emvododstat |
| Description | Emvododstat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target dihydroorotate dehydrogenase (quinone), mitochondrial. |
| Classification | Small molecule |
| Drug class | enzyme inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1ccc([C@H]2c3[nH]c4ccc(Cl)cc4c3CCN2C(=O)Oc2ccc(Cl)cc2)cc1 |
Identifiers
| PDB | — |
| CAS-ID | 1219951-09-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4650336 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 053QD2I96A (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
DHODH
DHODH
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Safety
Black-box Warning
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Adverse Events
0 adverse events reported
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