Elesclomol
Elesclomol is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Recurrence | D012008 | — | — | — | 1 | — | — | — | 1 |
| Carcinoma | D002277 | — | C80.0 | — | 1 | — | — | — | 1 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | 1 | — | — | — | 1 |
| Brenner tumor | D001948 | — | — | — | 1 | — | — | — | 1 |
| Endometrioid carcinoma | D018269 | — | — | — | 1 | — | — | — | 1 |
| Mucinous cystadenocarcinoma | D018282 | — | — | — | 1 | — | — | — | 1 |
| Mucinous adenocarcinoma | D002288 | — | — | — | 1 | — | — | — | 1 |
| Serous cystadenocarcinoma | D018284 | — | — | — | 1 | — | — | — | 1 |
| Fallopian tube neoplasms | D005185 | — | — | — | 1 | — | — | — | 1 |
| Transitional cell carcinoma | D002295 | — | — | — | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 2 | — | — | — | — | 2 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | — | — | — | — | 1 |
| Leukemia | D007938 | — | C95 | 1 | — | — | — | — | 1 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 1 | — | — | — | — | 1 |
| Myeloid leukemia | D007951 | — | C92 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alzheimer disease | D000544 | EFO_0000249 | F03 | — | — | — | — | 1 | 1 |
| Cognitive dysfunction | D060825 | — | G31.84 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Elesclomol |
| INN | elesclomol |
| Description | Elesclomol is a carbohydrazide obtained by formal condensation of the carboxy groups of malonic acid with the hydrino groups of two molar equivalents of N-methylbenzenecarbothiohydrazide It has a role as an antineoplastic agent and an apoptosis inducer. It is a carbohydrazide and a thiocarbonyl compound. It is functionally related to a malonic acid. |
| Classification | Small molecule |
| Drug class | heat-shock protein inducers, bimoclomal type |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CN(NC(=O)CC(=O)NN(C)C(=S)c1ccccc1)C(=S)c1ccccc1 |
Identifiers
| PDB | — |
| CAS-ID | 488832-69-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1972860 |
| ChEBI ID | 79369 |
| PubChem CID | 300471 |
| DrugBank | DB05719 |
| UNII ID | 6UK191M53P (ChemIDplus, GSRS) |
Target
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Trends
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Safety
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Adverse Events
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