Efaproxiral
Efaproxiral is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | — | 1 | 1 | — | — | 2 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | — | 1 | 1 | — | — | 2 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | — | — | 2 | — | — | 2 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | 1 | — | — | 1 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | — | — | 1 | — | — | 1 |
| Neoplasms | D009369 | — | C80 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Central nervous system neoplasms | D016543 | — | — | 1 | 1 | — | — | 1 | 2 |
| Nervous system neoplasms | D009423 | — | — | 1 | 1 | — | — | 1 | 2 |
| Glioma | D005910 | EFO_0000520 | — | 1 | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Efaproxiral |
| INN | efaproxiral |
| Description | Efaproxiral (INN) is an analogue of the cholesterol drug bezafibrate developed for the treatment of depression, traumatic brain injury, ischemia, stroke, myocardial infarction, diabetes, hypoxia, sickle cell disease, hypercholesterolemia and as a radio sensitiser.
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| Classification | Small molecule |
| Drug class | Fc fusion protein |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1cc(C)cc(NC(=O)Cc2ccc(OC(C)(C)C(=O)O)cc2)c1 |
Identifiers
| PDB | — |
| CAS-ID | 131179-95-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL18901 |
| ChEBI ID | — |
| PubChem CID | 122335 |
| DrugBank | — |
| UNII ID | J81E81G364 (ChemIDplus, GSRS) |
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Additional graphs summarizing 196 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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