Edrecolomab
Edrecolomab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target epithelial cell adhesion molecule.
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Events Timeline
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
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Completion date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| choline c 11 | New Drug Application | 2025-12-26 |
| zyrexal | unapproved drug other | 2020-02-10 |
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
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Patent Expiration
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HCPCS
No data
Clinical
Clinical Trials
811 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hereditary angioedemas | D054179 | EFO_0004131 | — | — | 6 | 4 | — | 2 | 10 |
| Angioedema | D000799 | EFO_0005532 | T78.3 | — | 4 | 4 | — | 2 | 8 |
| Inborn genetic diseases | D030342 | EFO_0000508 | — | — | 3 | 2 | — | — | 4 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Acute kidney injury | D058186 | — | N17 | — | 3 | — | — | — | 3 |
| Covid-19 | D000086382 | — | U07.1 | — | 2 | — | — | — | 2 |
| Kidney transplantation | D016030 | — | — | — | 1 | — | — | — | 1 |
| Graft rejection | D006084 | — | — | — | 1 | — | — | — | 1 |
| Myocardial infarction | D009203 | EFO_0000612 | I21 | — | 1 | — | — | — | 1 |
| Non-st elevated myocardial infarction | D000072658 | — | — | — | 1 | — | — | — | 1 |
| Infarction | D007238 | EFO_0009463 | — | — | 1 | — | — | — | 1 |
| Ischemic stroke | D000083242 | — | — | — | 1 | — | — | — | 1 |
| Aortic valve stenosis | D001024 | EFO_0000266 | — | — | 1 | — | — | — | 1 |
| Reperfusion injury | D015427 | — | — | — | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Renal insufficiency | D051437 | — | N19 | 1 | — | — | — | — | 1 |
| Delayed graft function | D051799 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Edrecolomab |
| INN | edrecolomab |
| Description | Edrecolomab (mouse mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108955 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB13375 |
| UNII ID | 0KYI9U9FSJ (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
EPCAM
EPCAM
Organism
Homo sapiens
Gene name
EPCAM
Gene synonyms
GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1
NCBI Gene ID
Protein name
epithelial cell adhesion molecule
Protein synonyms
Adenocarcinoma-associated antigen, CD326, Cell surface glycoprotein Trop-1, EGP, EGP314, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, hEGP314, human epithelial glycoprotein-2, KS 1/4 antigen, KSA, Major gastrointestinal tumor-associated protein GA733-2, membrane component, chromosome 4, surface marker (35kD glycoprotein), trophoblast cell surface antigen 1, Tumor-associated calcium signal transducer 1
Uniprot ID
Mouse ortholog
Epcam (17075)
epithelial cell adhesion molecule (Q99JW5)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 310,867 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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14,046 adverse events reported
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