Edrecolomab
Edrecolomab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target epithelial cell adhesion molecule.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| allevia | unapproved drug other | 2025-02-27 |
| choline c 11 | New Drug Application | 2024-12-17 |
| zyrexal | unapproved drug other | 2020-02-10 |
Indications
FDA
EMA
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Agency Specific
FDA
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Patent Expiration
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Clinical
Clinical Trials
91 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hyperlipidemias | D006949 | EFO_0003774 | E78.5 | — | — | — | 1 | — | 1 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 1 | 1 | — | 2 | 4 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | 1 | 1 | — | 1 | 3 |
| Adenocarcinoma | D000230 | — | — | 1 | — | 1 | — | 1 | 3 |
| Rectal neoplasms | D012004 | — | — | — | — | 1 | — | — | 1 |
| Hereditary nonpolyposis colorectal neoplasms | D003123 | EFO_0007354 | — | — | — | 1 | — | — | 1 |
| Syndrome | D013577 | — | — | — | — | 1 | — | — | 1 |
| Peutz-jeghers syndrome | D010580 | — | Q85.89 | — | — | 1 | — | — | 1 |
| Anesthesia | D000758 | — | — | — | 1 | 1 | — | — | 1 |
| Meningitis | D008581 | EFO_0000584 | G03 | — | — | 1 | — | — | 1 |
| Meningococcal meningitis | D008585 | EFO_1001040 | A39.0 | — | — | 1 | — | — | 1 |
Show 4 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 5 | 1 | — | — | 2 | 7 |
| Malaria | D008288 | EFO_0001068 | B54 | 5 | 1 | — | — | — | 5 |
| Carcinoma | D002277 | — | C80.0 | 1 | 2 | — | — | 1 | 3 |
| Colorectal neoplasms | D015179 | — | — | 1 | 1 | — | — | 1 | 3 |
| Falciparum malaria | D016778 | EFO_0007444 | B50 | 3 | 1 | — | — | — | 3 |
| Leukemia | D007938 | — | C95 | 1 | 1 | — | — | — | 2 |
| Lymphoma | D008223 | — | C85.9 | 1 | 1 | — | — | — | 2 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | — | 2 | — | — | — | 2 |
| Lymphoid leukemia | D007945 | — | C91 | — | 1 | — | — | 1 | 2 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | 1 | — | — | — | 2 |
Show 18 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 1 | — | — | — | 1 | 2 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 1 | — | — | — | 1 | 2 |
| Pneumococcal infections | D011008 | EFO_0000772 | J13 | 2 | — | — | — | — | 2 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 1 | — | — | — | 1 | 2 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 2 | — | — | — | — | 2 |
| Human influenza | D007251 | EFO_0007328 | J11.1 | 2 | — | — | — | — | 2 |
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Myelodysplastic syndromes | D009190 | — | D46 | 1 | — | — | — | — | 1 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 1 | — | — | — | — | 1 |
| Myeloid leukemia | D007951 | — | C92 | 1 | — | — | — | — | 1 |
Show 15 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Impacted tooth | D014095 | — | K01.1 | — | — | — | — | 7 | 7 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | — | — | 5 | 5 |
| Periodontal diseases | D010510 | — | K05.6 | — | — | — | — | 4 | 4 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 4 | 4 |
| Circulating neoplastic cells | D009360 | — | — | — | — | — | — | 3 | 3 |
| Dental caries | D003731 | EFO_0003819 | K02 | — | — | — | — | 3 | 3 |
| Lung neoplasms | D008175 | — | C34.90 | — | — | — | — | 3 | 3 |
| Atrophy | D001284 | — | — | — | — | — | — | 2 | 2 |
| Pulpitis | D011671 | EFO_1001139 | K04.0 | — | — | — | — | 2 | 2 |
| Alveolar bone loss | D016301 | — | — | — | — | — | — | 2 | 2 |
Show 63 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Edrecolomab |
| INN | edrecolomab |
| Description | Edrecolomab (mouse mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108955 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB13375 |
| UNII ID | 0KYI9U9FSJ (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
EPCAM
EPCAM
Organism
Homo sapiens
Gene name
EPCAM
Gene synonyms
GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1
NCBI Gene ID
Protein name
epithelial cell adhesion molecule
Protein synonyms
Adenocarcinoma-associated antigen, CD326, Cell surface glycoprotein Trop-1, EGP, EGP314, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, hEGP314, human epithelial glycoprotein-2, KS 1/4 antigen, KSA, Major gastrointestinal tumor-associated protein GA733-2, membrane component, chromosome 4, surface marker (35kD glycoprotein), trophoblast cell surface antigen 1, Tumor-associated calcium signal transducer 1
Uniprot ID
Mouse ortholog
Epcam (17075)
epithelial cell adhesion molecule (Q99JW5)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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14,048 adverse events reported
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