Tradename | Company | Number | Date | Products |
---|---|---|---|---|
GALLIUM GA 68 EDOTREOTIDE | University of Iowa | N-210828 RX | 2019-08-21 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
ga-68-dotatoc | New Drug Application | 2021-12-08 |
Expiration | Code | ||
---|---|---|---|
GALLIUM GA-68 EDOTREOTIDE, GALLIUM GA 68 EDOTREOTIDE, UIHC PET IMAGING | |||
2026-08-21 | ODE-383, W | ||
2024-08-21 | NCE, W |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neuroendocrine tumors | D018358 | EFO_1001901 | D3A.8 | 7 | 16 | 5 | — | 11 | 36 |
Pituitary neoplasms | D010911 | — | — | — | — | 1 | — | 1 | 2 |
Glioma | D005910 | EFO_0000520 | — | — | 1 | 1 | — | 1 | 2 |
Thymus neoplasms | D013953 | — | C37 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neuroblastoma | D009447 | EFO_0000621 | — | 3 | 7 | — | — | 2 | 10 |
Carcinoid tumor | D002276 | — | D3A.00 | 3 | 5 | — | — | 2 | 8 |
Medulloblastoma | D008527 | — | — | 1 | 5 | — | — | 2 | 7 |
Meningioma | D008579 | EFO_0003098 | D32.9 | 2 | 3 | — | — | 2 | 7 |
Paraganglioma | D010235 | — | — | 2 | 4 | — | — | 2 | 6 |
Pheochromocytoma | D010673 | — | — | 2 | 3 | — | — | 1 | 5 |
Insulinoma | D007340 | — | — | — | 1 | — | — | 1 | 2 |
Vipoma | D003969 | — | — | — | 1 | — | — | 1 | 2 |
Gastrinoma | D015408 | — | — | — | 1 | — | — | 1 | 2 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 1 | — | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Central nervous system neoplasms | D016543 | — | — | 2 | — | — | — | — | 2 |
Islet cell adenoma | D007516 | EFO_0007331 | D13.7 | 2 | — | — | — | — | 2 |
Von hippel-lindau disease | D006623 | — | Q85.83 | 1 | — | — | — | — | 1 |
Multiple endocrine neoplasia type 1 | D018761 | — | E31.21 | 1 | — | — | — | — | 1 |
Neoplasms | D009369 | — | C80 | 1 | — | — | — | — | 1 |
Sarcoma | D012509 | — | — | 1 | — | — | — | — | 1 |
Lymphoma | D008223 | — | C85.9 | 1 | — | — | — | — | 1 |
Melanoma | D008545 | — | — | 1 | — | — | — | — | 1 |
Paraneoplastic syndromes | D010257 | — | — | 1 | — | — | — | — | 1 |
Gastro-enteropancreatic neuroendocrine tumor | C535650 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Prostatic neoplasms | D011471 | — | C61 | — | — | — | — | 1 | 1 |
Small cell lung carcinoma | D055752 | — | — | — | — | — | — | 1 | 1 |
Merkel cell carcinoma | D015266 | EFO_1001471 | C4A | — | — | — | — | 1 | 1 |
Ganglioneuroma | D005729 | — | — | — | — | — | — | 1 | 1 |
Brain stem neoplasms | D020295 | EFO_1001767 | — | — | — | — | — | 1 | 1 |
Medullary carcinoma | D018276 | — | — | — | — | — | — | 1 | 1 |
Glucagonoma | D005935 | — | — | — | — | — | — | 1 | 1 |
Myocarditis | D009205 | — | I51.4 | — | — | — | — | 1 | 1 |
Brain neoplasms | D001932 | EFO_0003833 | C71 | — | — | — | — | 1 | 1 |
Glioblastoma | D005909 | EFO_0000515 | — | — | — | — | — | 1 | 1 |
Drug common name | Edotreotide |
INN | edotreotide |
Description | Edotreotide (USAN, also known as (DOTA0-Phe1-Tyr3) octreotide, DOTA-TOC, DOTATOC) is a substance which, when bound to various radionuclides, is used in the treatment and diagnosis of certain types of cancer. When used therapeutically it is an example of peptide receptor radionuclide therapy.
|
Classification | Small molecule |
Drug class | peptides: inhibition of growth hormone release |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)CN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)CSSC[C@@H](C(=O)N[C@H](CO)[C@@H](C)O)NC1=O |
PDB | — |
CAS-ID | 173606-11-6 |
RxCUI | — |
ChEMBL ID | CHEMBL408350 |
ChEBI ID | — |
PubChem CID | 158782 |
DrugBank | DB15494 |
UNII ID | U194AS08HZ (ChemIDplus, GSRS) |