EMODEPSIDE
Emodepside is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
8 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | 2 | — | — | — | 2 |
| Hookworm infections | D006725 | EFO_0007314 | B76 | — | 2 | — | — | — | 2 |
| Ancylostomiasis | D000724 | EFO_0007145 | B76.0 | — | 2 | — | — | — | 2 |
| Onchocerciasis | D009855 | EFO_0007402 | B73 | 1 | 1 | — | — | — | 2 |
| Communicable diseases | D003141 | — | — | — | 1 | — | — | — | 1 |
| Trichuriasis | D014257 | EFO_0007524 | — | — | 1 | — | — | — | 1 |
| Strongyloidiasis | D013322 | EFO_0007501 | B78 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Filariasis | D005368 | — | B74 | 2 | — | — | — | — | 2 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
| Blindness | D001766 | HP_0000618 | H53.12 | 1 | — | — | — | — | 1 |
| Ocular onchocerciasis | D015827 | EFO_0007398 | B73 | 1 | — | — | — | — | 1 |
| Helminthiasis | D006373 | EFO_1001342 | B65-B83 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | EMODEPSIDE |
| INN | emodepside |
| Description | Emodepside is a cyclooctadepsipeptide consisting of D-lactoyl, N-methyl-L-leucyl, 3-[4-(4-morpholinyl)phenyl]-D-lactoyl, N-methyl-L-leucyl, D-lactoyl, N-methyl-L-leucyl, 3-[4-(4-morpholinyl)phenyl]-D-lactoyl, and N-methyl-L-leucyl residues joined in sequence to give a 24-membered macrocycle. An anthelmintic, it is used with praziquantel for the treatment and control of hookworm, roundworm and tapeworm infections in cats. It has a role as an antinematodal drug. It is a semisynthetic derivative and a cyclooctadepsipeptide. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)C[C@H]1C(=O)O[C@H](Cc2ccc(N3CCOCC3)cc2)C(=O)N(C)[C@@H](CC(C)C)C(=O)O[C@H](C)C(=O)N(C)[C@@H](CC(C)C)C(=O)O[C@H](Cc2ccc(N3CCOCC3)cc2)C(=O)N(C)[C@@H](CC(C)C)C(=O)O[C@H](C)C(=O)N1C |
Identifiers
| PDB | — |
| CAS-ID | 155030-63-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2104404 |
| ChEBI ID | 78739 |
| PubChem CID | 6918632 |
| DrugBank | — |
| UNII ID | YZ647Y5GC9 (ChemIDplus, GSRS) |
Target
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Safety
Black-box Warning
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Adverse Events
0 adverse events reported
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