EMIVIRINE
Emivirine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 4 | — | — | 1 | 5 |
| Infections | D007239 | EFO_0000544 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | EMIVIRINE |
| INN | emivirine |
| Description | Emivirine is a pyrimidone that is uracil which is substituted at positions 1, 5 and 6 by ethoxymethyl, isopropyl, and benzyl groups, respectively. A non-nucleoside inhibitor of HIV-1 reverse transcriptase, emivirine was an unsuccessful experimental agent for the treatment of HIV. It has a role as a HIV-1 reverse transcriptase inhibitor and an antiviral drug. It is functionally related to a uracil. |
| Classification | Small molecule |
| Drug class | antivirals: non-nucleoside reverse transcriptase inhibitors, not benzoxazinone derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCOCn1c(Cc2ccccc2)c(C(C)C)c(=O)[nH]c1=O |
Identifiers
| PDB | — |
| CAS-ID | 149950-60-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL35033 |
| ChEBI ID | 44143 |
| PubChem CID | 65013 |
| DrugBank | — |
| UNII ID | X87G8IX72O (ChemIDplus, GSRS) |
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Trends
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Safety
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