ELUBRIXIN
Elubrixin is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against C-X-C chemokine receptor type 2.
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Events Timeline
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YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fibrosis | D005355 | — | — | 1 | 1 | — | — | — | 2 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | 1 | 1 | — | — | — | 2 |
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | 1 | — | — | — | 1 |
| Colitis | D003092 | EFO_0003872 | K52.9 | — | 1 | — | — | — | 1 |
| Ulcer | D014456 | MPATH_579 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 3 | — | — | — | — | 3 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ELUBRIXIN |
| INN | elubrixin |
| Description | Elubrixin is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against C-X-C chemokine receptor type 2. |
| Classification | Small molecule |
| Drug class | chemokine (C-X-C motif) receptor 2 (CXCR2) modulators |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C(Nc1ccc(Cl)c(S(=O)(=O)N2CCNCC2)c1O)Nc1cccc(F)c1Cl |
Identifiers
| PDB | — |
| CAS-ID | 688763-64-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2178579 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | MW2AIJ8USP (ChemIDplus, GSRS) |
Target
Agency Approved
CXCR2
CXCR2
Organism
Homo sapiens
Gene name
CXCR2
Gene synonyms
IL8RB
NCBI Gene ID
Protein name
C-X-C chemokine receptor type 2
Protein synonyms
CD182, CDw128b, chemokine (CXC) receptor 2, CXC-R2, CXCR-2, CXCR2 gene for IL8 receptor type B, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8 receptor type 2, IL-8R B, interleukin 8 receptor type 2, interleukin 8 receptor, beta, interleukin-8 receptor type B
Uniprot ID
Mouse ortholog
Cxcr2 (12765)
C-X-C chemokine receptor type 2 (Q53X27)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 25 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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