ELGEMTUMAB
Elgemtumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against receptor tyrosine-protein kinase erbB-3.
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FDA approval date
EMA approval date
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Study first post date
Last update post date
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Commercial
No data
Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 3 | 1 | — | — | — | 3 |
| Squamous cell carcinoma | D002294 | — | — | 3 | 1 | — | — | — | 3 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 2 | 1 | — | — | — | 2 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 3 | — | — | — | — | 3 |
| Esophageal squamous cell carcinoma | D000077277 | — | — | 2 | — | — | — | — | 2 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 2 | — | — | — | — | 2 |
| Neoplasms | D009369 | — | C80 | 1 | — | — | — | — | 1 |
| Squamous cell neoplasms | D018307 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ELGEMTUMAB |
| INN | elgemtumab |
| Description | Elgemtumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against receptor tyrosine-protein kinase erbB-3. |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4298013 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 5F1CN52GFM (ChemIDplus, GSRS) |
Target
Agency Approved
ERBB3
ERBB3
Organism
Homo sapiens
Gene name
ERBB3
Gene synonyms
HER3
NCBI Gene ID
Protein name
receptor tyrosine-protein kinase erbB-3
Protein synonyms
human epidermal growth factor receptor 3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Uniprot ID
Mouse ortholog
Erbb3 (13867)
receptor tyrosine-protein kinase erbB-3 (Q8K317)
Alternate
No data
Variants
No data
Financial
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Trends
PubMed Central
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Additional graphs summarizing 145 documents
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Safety
Black-box Warning
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Adverse Events
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