ELEZANUMAB
Elezanumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against repulsive guidance molecule A.
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Commercial
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Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | 2 | 2 | — | — | — | 4 |
| Sclerosis | D012598 | — | — | 2 | 2 | — | — | — | 4 |
| Ischemic stroke | D000083242 | — | — | — | 1 | — | — | 1 | 2 |
| Spinal cord injuries | D013119 | EFO_1001919 | — | — | 1 | — | — | 1 | 2 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | 1 | — | — | — | 1 |
| Ischemia | D007511 | EFO_0000556 | — | — | 1 | — | — | — | 1 |
| Cerebral infarction | D002544 | — | I63 | — | 1 | — | — | — | 1 |
| Wounds and injuries | D014947 | — | T14.8 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ELEZANUMAB |
| INN | elezanumab |
| Description | Elezanumab (development names AE12-1Y-QL and ABT-555) is a fully human monoclonal antibody developed by AbbVie against repulsive guidance molecule A (RGMa). It has been tested in people with multiple sclerosis and acute ischemic stroke.
|
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297743 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | SK1LVT23A1 (ChemIDplus, GSRS) |
Target
Agency Approved
RGMA
RGMA
Alternate
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Safety
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Adverse Events
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