Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 2 | 1 | — | — | — | 3 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 2 | 1 | — | — | — | 3 |
Obesity | D009765 | EFO_0001073 | E66.9 | 1 | 1 | — | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Overweight | D050177 | — | E66.3 | 1 | — | — | — | — | 1 |
Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | 1 | — | — | — | — | 1 |
Renal insufficiency | D051437 | — | N19 | 1 | — | — | — | — | 1 |
Drug common name | EFINOPEGDUTIDE |
INN | efinopegdutide |
Description | Efinopegdutide (MK-6024) is a dual agonist of the glucagon and GLP-1 receptors. It is being developed by Merck for non-alcoholic fatty liver disease. It was also developed for type 2 diabetes and obesity but these indications were discontinued.
|
Classification | Protein |
Drug class | Fc fusion protein; peptides: oxyntomodulin analogs; PEGylated compounds, covalent attachment of macrogol (polyethylene glycol) polymer |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL4297576 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | — |
UNII ID | DR6P1M58PO (ChemIDplus, GSRS) |