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Drug ReportsE-7386
E-7386
E-7386 is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Colorectal neoplasmsD015179323
Hepatocellular carcinomaD006528C22.0323
NeoplasmsD009369C80212
Liver neoplasmsD008113EFO_1001513C22.0222
Endometrial neoplasmsD016889EFO_0004230111
MelanomaD008545111
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients22
Digestive system neoplasmsD00406711
Gastrointestinal stromal tumorsD046152EFO_0000505C49.A11
Soft tissue neoplasmsD01298311
Adrenocortical carcinomaD01826811
Desmoid tumorsD018222D48.1111
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameE-7386
INNpegamotecan
Description
E-7386 is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
Classification
Small molecule
Drug class
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Structure (InChI/SMILES or Protein Sequence)
C=CCN1CC(=O)N2[C@@H](Cc3ccc(O)cc3F)C(=O)N(Cc3cccc(N4CC(N5CCN(CC)CC5)C4)n3)C[C@@H]2N1C(=O)NCc1ccccc1
Identifiers
PDB
CAS-ID1799824-08-0
RxCUI
ChEMBL IDCHEMBL4297491
ChEBI ID
PubChem CID
DrugBank
UNII IDZY7ZTE7LFH (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 71 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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18 adverse events reported
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