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Drug ReportsDyclonine
Dyclonine
Dyclopro (dyclonine) is a small molecule pharmaceutical. Dyclonine was first approved as Dyclone on 1982-01-01. It is used to treat facial pain in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Dyclopro (discontinued: Dyclone)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Dyclonine hydrochloride
Tradename
Company
Number
Date
Products
DYCLONEAstraZenecaN-009925 DISCN1982-01-01
2 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
ambix first aidOTC monograph not final2019-11-04
benzethonium chloride and dyclonine hydrochlorideC2002632024-02-09
benzethonium chloride plus dyclonine hydrochlorideC2002632024-10-11
dycloproANDA2024-10-23
leader liquid bandageC2002632024-11-01
liquid bandageC2002632024-10-14
premier solutions liquid bandageC2002632024-10-14
skin shieldOTC monograph not final2010-06-22
sucretsC2002632024-03-20
sucrets completeOTC monograph not final2009-08-04
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Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
facial pain—D005157R51.9
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N01: Anesthetics
— N01B: Local anesthetics
— N01BX: Other local anesthetics in atc
— N01BX02: Dyclonine
R: Respiratory system drugs
— R02: Throat preparations
— R02A: Throat preparations
— R02AD: Local anesthetic throat preparations
— R02AD04: Dyclonine
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AdenomaD000236—————1—1
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Gastrointestinal diseasesD005767——————11
Digestive system diseasesD004066HP_0011024K92.9————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDyclonine
INNdyclonine
Description
Dyclonine is n-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group. It has a role as a topical anaesthetic. It is a member of piperidines and an aromatic ketone.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCCCOc1ccc(C(=O)CCN2CCCCC2)cc1
Identifiers
PDB—
CAS-ID586-60-7
RxCUI—
ChEMBL IDCHEMBL1201217
ChEBI ID4724
PubChem CID3180
DrugBankDB00645
UNII ID078A24Q30O (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 315 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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41 adverse events reported
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