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Drug ReportsDyclonine
Dyclonine
Dyclopro (dyclonine) is a small molecule pharmaceutical. Dyclonine was first approved as Dyclone on 1982-01-01. It is used to treat facial pain in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Dyclonine hydrochloride
Tradename
Company
Number
Date
Products
DYCLONEAstraZenecaN-009925 DISCN1982-01-01
2 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
ambix first aidOTC monograph not final2019-11-04
benzethonium chloride and dyclonine hydrochlorideC2002632024-02-09
benzethonium chloride plus dyclonine hydrochlorideC2002632024-05-01
dycloproANDA2022-01-06
leader liquid bandageC2002632024-02-21
liquid bandageC2002632024-04-11
premier solutions liquid bandageC2002632024-02-01
skin shieldOTC monograph not final2010-06-22
sucretsC2002632024-03-20
sucrets completeOTC monograph not final2009-08-04
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Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
facial pain—D005157R51.9
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N01: Anesthetics
— N01B: Local anesthetics
— N01BX: Other local anesthetics in atc
— N01BX02: Dyclonine
R: Respiratory system drugs
— R02: Throat preparations
— R02A: Throat preparations
— R02AD: Local anesthetic throat preparations
— R02AD04: Dyclonine
HCPCS
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Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AdenomaD000236—————1—1
Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Gastrointestinal diseasesD005767——————11
Digestive system diseasesD004066HP_0011024K92.9————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDyclonine
INNdyclonine
Description
Dyclonine is n-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group. It has a role as a topical anaesthetic. It is a member of piperidines and an aromatic ketone.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCCCOc1ccc(C(=O)CCN2CCCCC2)cc1
Identifiers
PDB—
CAS-ID586-60-7
RxCUI—
ChEMBL IDCHEMBL1201217
ChEBI ID4724
PubChem CID3180
DrugBankDB00645
UNII ID078A24Q30O (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 311 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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41 adverse events reported
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