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Drug ReportsDuvoglustat
Duvoglustat
Duvoglustat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target lysosomal alpha-glucosidase.
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Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
No data
Commercial
No data
Clinical
No data
Drug
General
Drug common nameDuvoglustat
INNduvoglustat
Description
Duvoglustat is an optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration. It has a role as an EC 3.2.1.20 (alpha-glucosidase) inhibitor, an anti-HIV agent, an anti-obesity agent, a bacterial metabolite, a hypoglycemic agent, a hepatoprotective agent and a plant metabolite. It is a 2-(hydroxymethyl)piperidine-3,4,5-triol and a piperidine alkaloid.
Classification
Small molecule
Drug classenzyme inhibitors: glucosyltransferase inhibitors
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Identifiers
PDB
CAS-ID19130-96-2
RxCUI
ChEMBL IDCHEMBL307429
ChEBI ID44369
PubChem CID29435
DrugBankDB03206
UNII IDFZ56898FLE (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
GAA
GAA
Organism
Homo sapiens
Gene name
GAA
Gene synonyms
NCBI Gene ID
Protein name
lysosomal alpha-glucosidase
Protein synonyms
Acid maltase, Aglucosidase alfa, glucosidase alpha, acid
Uniprot ID
Mouse ortholog
Gaa (14387)
lysosomal alpha-glucosidase (Q91Z45)
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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