Dulanermin
Dulanermin is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
39 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Thrombocytopenic purpura idiopathic | D016553 | EFO_0007160 | D69.3 | — | 2 | 2 | — | — | 4 |
| Thrombocytopenia | D013921 | HP_0001873 | D69.6 | — | 2 | 2 | — | — | 4 |
| Non-small-cell lung carcinoma | D002289 | — | — | — | 1 | 1 | — | — | 2 |
| Lung neoplasms | D008175 | — | C34.90 | — | 1 | 1 | — | — | 2 |
| Anemia | D000740 | EFO_0004272 | D64.9 | — | 1 | 1 | — | — | 2 |
| Hemolysis | D006461 | — | — | — | 1 | 1 | — | — | 2 |
| Hemolytic anemia autoimmune | D000744 | EFO_1001264 | D59.10 | — | 1 | 1 | — | — | 2 |
| Hemolytic anemia | D000743 | — | D55-D59 | — | 1 | 1 | — | — | 2 |
| Neuromyelitis optica | D009471 | EFO_0004256 | G36.0 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | 6 | 1 | — | — | — | 6 |
| Systemic scleroderma | D012595 | EFO_0000717 | M34 | — | 3 | — | — | 2 | 5 |
| Diffuse scleroderma | D045743 | EFO_0000404 | — | — | 3 | — | — | 2 | 5 |
| Sclerosis | D012598 | — | — | — | 4 | — | — | 1 | 5 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 5 | 1 | — | — | — | 5 |
| Systemic lupus erythematosus | D008180 | EFO_0002690 | M32 | 1 | 1 | — | — | 1 | 3 |
| Leukemia | D007938 | — | C95 | 3 | 1 | — | — | — | 3 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 2 | 1 | — | — | — | 2 |
| Psychologic desensitization | D003887 | — | — | — | 1 | — | — | — | 1 |
| B-cell leukemia | D015448 | — | — | 1 | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| B-cell lymphoma | D016393 | — | — | 4 | — | — | — | — | 4 |
| Colorectal neoplasms | D015179 | — | — | 2 | — | — | — | — | 2 |
| Lymphoid leukemia | D007945 | — | C91 | 2 | — | — | — | — | 2 |
| B-cell lymphoma marginal zone | D018442 | — | C88.4 | 2 | — | — | — | — | 2 |
| Follicular lymphoma | D008224 | — | C82 | 2 | — | — | — | — | 2 |
| Mantle-cell lymphoma | D020522 | — | C83.1 | 2 | — | — | — | — | 2 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 2 | — | — | — | — | 2 |
| Neoplasms | D009369 | — | C80 | 1 | — | — | — | — | 1 |
| Lymphopenia | D008231 | — | D72.810 | 1 | — | — | — | — | 1 |
| Idiopathic cd4-positive t-lymphocytopenia | D018344 | EFO_0007322 | — | 1 | — | — | — | — | 1 |
Show 11 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Localized scleroderma | D012594 | EFO_1001361 | L94.0 | — | — | — | — | 2 | 2 |
| Hyperprolactinemia | D006966 | — | E22.1 | — | — | — | — | 1 | 1 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | — | — | 1 | 1 |
| Kidney transplantation | D016030 | — | — | — | — | — | — | 1 | 1 |
| Graft rejection | D006084 | — | — | — | — | — | — | 1 | 1 |
| Fever | D005334 | — | R50.9 | — | — | — | — | 1 | 1 |
| Virus diseases | D014777 | — | B34 | — | — | — | — | 1 | 1 |
| Hyperthermia | D000084462 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Dulanermin |
| INN | dulanermin |
| Description | Dulanermin is a protein pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Protein |
| Drug class | growth factors: tumor necrosis factors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107846 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | L65E7T81M5 (ChemIDplus, GSRS) |
Target
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Safety
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Adverse Events
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