Therapeutic Area | MeSH |
---|---|
nervous system diseases | D009422 |
cardiovascular diseases | D002318 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
orthostatic hypotension | — | D007024 | I95.1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Parkinson disease | D010300 | EFO_0002508 | G20 | — | 2 | — | 3 | 1 | 6 |
Hypotension | D007022 | EFO_0005251 | I95 | — | 1 | — | 3 | — | 4 |
Orthostatic hypotension | D007024 | — | I95.1 | — | 1 | — | 3 | — | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Shy-drager syndrome | D012791 | EFO_1001050 | — | — | 1 | — | — | — | 1 |
Multiple system atrophy | D019578 | — | — | — | 1 | — | — | — | 1 |
Fatigue | D005221 | — | R53.83 | — | 1 | — | — | — | 1 |
Parkinsonian disorders | D020734 | — | G20.C | — | 1 | — | — | — | 1 |
Progressive supranuclear palsy | D013494 | EFO_0002512 | G23.1 | — | 1 | — | — | — | 1 |
Postural orthostatic tachycardia syndrome | D054972 | — | G90.A | — | 1 | — | — | — | 1 |
Vasovagal syncope | D019462 | — | R55 | — | 1 | — | — | — | 1 |
Tachycardia | D013610 | — | R00.0 | — | 1 | — | — | — | 1 |
Syncope | D013575 | — | G90.01 | — | 1 | — | — | — | 1 |
Syndrome | D013577 | — | — | — | 1 | — | — | — | 1 |
Drug common name | Droxidopa |
INN | droxidopa |
Description | Droxidopa is a serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension It has a role as a prodrug, a vasoconstrictor agent and an antihypertensive agent. It is a L-tyrosine derivative and a member of catechols. |
Classification | Small molecule |
Drug class | dopamine receptor agonists |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | N[C@H](C(=O)O)[C@H](O)c1ccc(O)c(O)c1 |
PDB | — |
CAS-ID | 23651-95-8 |
RxCUI | — |
ChEMBL ID | CHEMBL2103827 |
ChEBI ID | 31524 |
PubChem CID | 92974 |
DrugBank | DB06262 |
UNII ID | J7A92W69L7 (ChemIDplus, GSRS) |