Doxribtimine
Doxribtimine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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2Y
5Y
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Events
FDA approval date
EMA approval date
Patent expiration date
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Commercial
No data
Clinical
Clinical Trials
643 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | 2 | 3 | 2 | 3 | 6 | 16 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | 1 | 1 | 2 |
| Hemophilia a | D006467 | EFO_0007267 | D66 | — | — | — | 1 | — | 1 |
| Hemophilia b | D002836 | — | D67 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic hepatitis b | D019694 | EFO_0004239 | B18.1 | — | — | 2 | — | — | 2 |
| Colorectal neoplasms | D015179 | — | — | — | — | 1 | — | — | 1 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | 1 | — | — | 1 |
| Fibrosis | D005355 | — | — | — | — | 1 | — | — | 1 |
| Hepatitis b | D006509 | — | — | — | — | 1 | — | — | 1 |
| Hepatitis | D006505 | — | K75.9 | — | — | 1 | — | — | 1 |
| Hepatitis a | D006506 | EFO_0007305 | B15 | — | — | 1 | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 2 | — | — | — | 1 | 3 |
| Aids-related complex | D000386 | EFO_0007137 | B20 | 1 | — | — | — | 1 | 2 |
| Hepatitis c | D006526 | — | B19.2 | 1 | — | — | — | — | 1 |
| Aids-related opportunistic infections | D017088 | — | — | 1 | — | — | — | — | 1 |
| Tropical spastic paraparesis | D015493 | EFO_0007527 | G04.1 | 1 | — | — | — | — | 1 |
| Htlv-i infections | D015490 | EFO_0007316 | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cytomegalovirus retinitis | D017726 | EFO_1001302 | — | — | — | — | — | 1 | 1 |
| Retinitis | D012173 | — | H30.9 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Doxribtimine |
| INN | doxribtimine |
| Description | 1-(2-Deoxypentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione is a pyrimidine 2'-deoxyribonucleoside. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O |
Identifiers
| PDB | — |
| CAS-ID | 50-89-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL52609 |
| ChEBI ID | 17748 |
| PubChem CID | 1134 |
| DrugBank | DB04485 |
| UNII ID | VC2W18DGKR (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
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Trends
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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105 adverse events reported
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