Therapeutic Area | MeSH |
---|---|
urogenital diseases | D000091642 |
cardiovascular diseases | D002318 |
Brand Name | Status | Last Update |
---|---|---|
cardura | New Drug Application | 2023-05-15 |
cardura xl | New Drug Application | 2010-03-24 |
doxazosin | ANDA | 2024-01-22 |
doxazosin doxazosin mesylate | NDA authorized generic | 2022-01-20 |
doxazosin mesylate | ANDA | 2024-01-23 |
ibuprofen | ANDA | 2022-01-27 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
hypertension | EFO_0000537 | D006973 | I10 |
prostatic hyperplasia | EFO_0000284 | D011470 | N40 |
urinary retention | HP_0000016 | D016055 | R33 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypertension | D006973 | EFO_0000537 | I10 | 1 | 2 | 2 | 8 | 9 | 21 |
Prostatic hyperplasia | D011470 | EFO_0000284 | N40 | — | 2 | 1 | 2 | 10 | 15 |
Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | 1 | 3 | — | 1 | — | 5 |
Cardiovascular diseases | D002318 | HP_0001626 | — | — | 1 | 1 | 1 | 1 | 4 |
Pheochromocytoma | D010673 | — | — | — | — | 1 | 1 | 1 | 3 |
Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | 1 | 1 | 2 |
Essential hypertension | D000075222 | — | I10 | — | — | — | 2 | — | 2 |
Diabetic nephropathies | D003928 | EFO_0000401 | — | — | — | 1 | 1 | — | 2 |
Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | — | 1 | 1 | — | 2 |
Chronic renal insufficiency | D051436 | — | N18 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Coronary disease | D003327 | — | — | — | — | 1 | — | 2 | 3 |
Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 1 | 1 | — | 1 | 3 |
Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | 1 | — | 1 | 2 |
Kidney calculi | D007669 | EFO_0004253 | N20 | — | — | 1 | — | 1 | 2 |
Heart failure | D006333 | HP_0001635 | I50 | — | — | 1 | — | — | 1 |
Hypercholesterolemia | D006937 | HP_0003124 | — | — | — | 1 | — | — | 1 |
Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | 1 | — | — | 1 |
Paraganglioma | D010235 | — | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cocaine-related disorders | D019970 | — | F14 | 4 | 3 | — | — | — | 6 |
Alcoholism | D000437 | EFO_0003829 | F10.1 | 1 | 4 | — | — | — | 5 |
Opioid-related disorders | D009293 | EFO_0005611 | F11 | — | 1 | — | — | — | 1 |
Vascular diseases | D014652 | EFO_0004264 | I77 | — | 1 | — | — | — | 1 |
Smoking | D012907 | EFO_0004318 | — | — | 1 | — | — | — | 1 |
Anxiety | D001007 | EFO_0005230 | F41.1 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Substance-related disorders | D019966 | EFO_0003890 | F13 | 3 | — | — | — | — | 3 |
Erectile dysfunction | D007172 | EFO_0004234 | F52.21 | 1 | — | — | — | 1 | 2 |
Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Amphetamine-related disorders | D019969 | EFO_0004701 | F15 | 1 | — | — | — | — | 1 |
Mood disorders | D019964 | EFO_0004247 | F30-F39 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Urolithiasis | D052878 | — | N20-N23 | — | — | — | — | 2 | 2 |
Covid-19 | D000086382 | — | U07.1 | — | — | — | — | 1 | 1 |
Microvascular angina | D017566 | — | — | — | — | — | — | 1 | 1 |
Urinary retention | D016055 | HP_0000016 | R33 | — | — | — | — | 1 | 1 |
Hyperaldosteronism | D006929 | HP_0011736 | E26 | — | — | — | — | 1 | 1 |
Drug common name | Doxazosin |
INN | doxazosin |
Description | Doxazosin is a member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure. It has a role as an antihypertensive agent, an alpha-adrenergic antagonist, an antineoplastic agent, a vasodilator agent and an antihyperplasia drug. It is a member of quinazolines, a N-acylpiperazine, a N-arylpiperazine, a benzodioxine, a monocarboxylic acid amide and an aromatic amine. |
Classification | Small molecule |
Drug class | antihypertensives (prazosin type) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | COc1cc2nc(N3CCN(C(=O)C4COc5ccccc5O4)CC3)nc(N)c2cc1OC |
PDB | — |
CAS-ID | 74191-85-8 |
RxCUI | — |
ChEMBL ID | CHEMBL707 |
ChEBI ID | 4708 |
PubChem CID | 3157 |
DrugBank | DB00590 |
UNII ID | NW1291F1W8 (ChemIDplus, GSRS) |