Doribax(doripenem)
Doribax (doripenem) is a small molecule pharmaceutical. Doripenem was first approved as Doribax on 2007-10-12. It is used to treat bacterial infections, intraabdominal infections, and urinary tract infections in the USA. It has been approved in Europe to treat bacterial infections, bacterial pneumonia, cross infection, urinary tract infections, and ventilator-associated pneumonia.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| urinary tract infections | EFO_0003103 | D014552 | N39.0 |
| bacterial infections | — | D001424 | A49 |
| intraabdominal infections | — | D059413 | — |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| J1267 | Injection, doripenem, 10 mg |
Clinical
Clinical Trials
31 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | 1 | 7 | 1 | — | 9 |
| Pneumonia | D011014 | EFO_0003106 | — | — | 1 | 4 | 1 | — | 6 |
| Ventilator-associated pneumonia | D053717 | EFO_1001865 | J95.851 | — | 1 | 3 | 1 | — | 5 |
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | — | 3 | 1 | — | 4 |
| Sepsis | D018805 | HP_0100806 | A41.9 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Communicable diseases | D003141 | — | — | — | 1 | 7 | — | — | 8 |
| Bacterial infections | D001424 | — | A49 | 1 | 1 | 2 | — | — | 4 |
| Intraabdominal infections | D059413 | — | — | — | 1 | 3 | — | — | 4 |
| Pyelonephritis | D011704 | EFO_1001141 | N10-N16 | — | — | 3 | — | — | 3 |
| Appendicitis | D001064 | EFO_0007149 | K37 | — | — | 3 | — | — | 3 |
| Peritonitis | D010538 | EFO_0008588 | K65 | — | — | 3 | — | — | 3 |
| Bacterial pneumonia | D018410 | EFO_1001272 | J15.9 | — | 1 | 1 | — | — | 2 |
| Abdominal abscess | D018784 | EFO_1001753 | — | — | 1 | 1 | — | — | 2 |
| Mycoses | D009181 | — | B35-B49 | — | — | 2 | — | — | 2 |
| Pancreatitis | D010195 | HP_0001733 | K85 | — | — | 2 | — | — | 2 |
Show 13 more
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Meningitis | D008581 | HP_0001287 | G03 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Doripenem |
| INN | doripenem |
| Description | Doripenem is a member of carbapenems. |
| Classification | Small molecule |
| Drug class | antibacterial antibiotics, carbapenem derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(S[C@@H]3CN[C@H](CNS(N)(=O)=O)C3)[C@H](C)[C@H]12 |
Identifiers
| PDB | — |
| CAS-ID | 148016-81-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL491571 |
| ChEBI ID | — |
| PubChem CID | 73303 |
| DrugBank | — |
| UNII ID | BHV525JOBH (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 4,282 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
1,043 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use