Docosanol
Abreva, Docosanol (docosanol) is a small molecule pharmaceutical. Docosanol was first approved as Abreva on 2000-07-25. It is used to treat blister in the USA.
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Commercial
Therapeutic Areas
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Abreva, Docosanol
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| abreva | ANDA | 2024-06-20 |
| cold sore fever blister | ANDA | 2024-09-25 |
| cold sore fever blister treatment | ANDA | 2024-10-17 |
| cold sore treatment | ANDA | 2023-11-30 |
| docosanol | ANDA | 2024-10-01 |
| julie cold sore treatment | ANDA | 2024-07-19 |
Agency Specific
FDA
EMA
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Herpes simplex | D006561 | — | B00 | — | 3 | — | 1 | — | 4 |
| Herpes labialis | D006560 | EFO_1001347 | B00.1 | — | 2 | — | 1 | — | 3 |
Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Herpetic stomatitis | D013283 | EFO_0007307 | — | — | 2 | — | — | — | 2 |
| Recurrence | D012008 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Skin abnormalities | D012868 | HP_0000951 | Q82.9 | — | — | — | — | 1 | 1 |
| Skin aging | D015595 | EFO_0005422 | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Docosanol |
| INN | — |
| Description | Docosan-1-ol is a long-chain primary fatty alcohol that is docosane substituted by a hydroxy group at position 1. It has a role as an antiviral agent. It is a long-chain primary fatty alcohol and a fatty alcohol 22:0. It derives from a hydride of a docosane. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCCCCCCCCCCCCCCCCCCCO |
Identifiers
| PDB | — |
| CAS-ID | 661-19-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1200453 |
| ChEBI ID | 31000 |
| PubChem CID | 12620 |
| DrugBank | DB00632 |
| UNII ID | — |
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Estimated US medical usage
Docosanol
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Trends
PubMed Central
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Additional graphs summarizing 497 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
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13,760 adverse events reported
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