Therapeutic Area | MeSH |
---|---|
eye diseases | D005128 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
open-angle glaucoma | EFO_0004190 | D005902 | H40.1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypertension | D006973 | EFO_0000537 | I10 | — | — | 1 | — | — | 1 |
Ocular hypertension | D009798 | EFO_1001069 | H40.0 | — | — | 1 | — | — | 1 |
Glaucoma | D005901 | EFO_0000516 | H40 | — | — | 1 | — | — | 1 |
Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | — | — | 1 | — | — | 1 |
Cataract | D002386 | EFO_0001059 | H26.9 | — | — | 1 | — | — | 1 |
Drug common name | Dipivefrin |
INN | dipivefrine |
Description | Dipivefrin is the dipivalate ester of (+-)-epinephrine (racepinephrine). A pro-drug of epinephrine, the hydrochloride is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. It has a role as a prodrug, an adrenergic agonist, a sympathomimetic agent, an antiglaucoma drug and an ophthalmology drug. It is a member of ethanolamines and a pivalate ester. It is functionally related to an adrenaline. It is a conjugate base of a dipivefrin(1+). |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1 |
PDB | — |
CAS-ID | 52365-63-6 |
RxCUI | — |
ChEMBL ID | CHEMBL1201262 |
ChEBI ID | 4646 |
PubChem CID | 3105 |
DrugBank | DB00449 |
UNII ID | 8Q1PVL543G (ChemIDplus, GSRS) |